Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Unit 1463, 1400 Pressler Street, Houston, TX 77030, USA.
Best Pract Res Clin Haematol. 2013 Sep;26(3):301-6. doi: 10.1016/j.beha.2013.10.012. Epub 2013 Oct 16.
At present, a number of invasive diagnostic techniques can be used to diagnose the cause of lung infiltrates in patients with hematologic malignancies or hematopoietic stem cell transplantation recipients. Bronchoscopy with measurement of biomarkers in the bronchoalveolar lavage (BAL) will most likely become the preferred method to diagnose infectious causes of pulmonary infiltrates. However, there is no uniform approach regarding the technical parameters of the lavage procedure in cancer patients. Diagnostic protocols vary by region, center, and the expertise of the staff. This mini review discusses the issues surrounding diffuse pulmonary infiltrates and provides some recommendations to deal with these issues.
目前,有一些侵袭性诊断技术可用于诊断血液恶性肿瘤或造血干细胞移植受者肺部浸润的原因。支气管镜检查并测量支气管肺泡灌洗液(BAL)中的生物标志物,很可能成为诊断肺部浸润感染性病因的首选方法。然而,癌症患者灌洗术的技术参数尚无统一方法。诊断方案因地区、中心和工作人员的专业知识而异。本综述讨论了弥漫性肺部浸润的相关问题,并提出了一些处理这些问题的建议。