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精神分裂症、重性抑郁症和分裂情感性障碍中快感缺失与冲动之间的关系。

Relationship between anhedonia and impulsivity in schizophrenia, major depression and schizoaffective disorder.

机构信息

Department of Psychiatry, College of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

Asian J Psychiatr. 2013 Dec;6(6):577-80. doi: 10.1016/j.ajp.2013.09.002. Epub 2013 Sep 12.

DOI:10.1016/j.ajp.2013.09.002
PMID:24309876
Abstract

BACKGROUND

Anhedonia and impulsivity are prominent symptoms of many psychiatric disorders and may indicate worse prognosis, notably in schizophrenia and major depression. Despite the convergence of negative outcomes from both dimensions, the relationship between anhedonia and impulsivity in psychiatric disorders has been seldom directly assessed. The objective of the present study is to examine the correlations between anhedonia and impulsivity in three diagnostic groups: major depression, schizophrenia and schizoaffective disorder.

SAMPLING AND METHODS

121 outpatients (Mansoura University Hospital, Egypt) with major depressive disorder (N=29), schizophrenia (N=59), and schizoaffective disorder (N=33), were assessed and responded to the Beck Depression Inventory, Barrat's Impulsivity Scale-11, and Chapman's Social and Physical Anhedonia Scales.

RESULTS

Physical and social anhedonia scores were negatively correlated to impulsivity scores in major depression patients. Conversely, higher scores in physical and social anhedonia predicted higher impulsivity scores in schizophrenia. No correlations between impulsivity and anhedonia were evidenced among schizoaffectives.

CONCLUSION

The relationship between self-reported physical and social anhedonia and impulsivity is diagnosis-specific.

摘要

背景

快感缺失和冲动是许多精神障碍的突出症状,可能预示着更糟糕的预后,尤其是在精神分裂症和重度抑郁症中。尽管这两个维度的负面结果趋同,但快感缺失和冲动在精神障碍中的关系很少被直接评估。本研究的目的是在三个诊断组(重度抑郁症、精神分裂症和分裂情感障碍)中检查快感缺失和冲动之间的相关性。

方法

对 121 名门诊患者(埃及曼苏拉大学医院)进行评估,他们分别患有重度抑郁症(N=29)、精神分裂症(N=59)和分裂情感障碍(N=33),并对他们进行了贝克抑郁量表、巴雷特冲动量表-11 和查普曼的社会和身体快感缺失量表的评估。

结果

在重度抑郁症患者中,身体和社会快感缺失评分与冲动评分呈负相关。相反,身体和社会快感缺失的得分越高,预示着精神分裂症患者的冲动得分越高。在分裂情感障碍患者中,没有发现冲动和快感缺失之间的相关性。

结论

自我报告的身体和社会快感缺失与冲动之间的关系具有诊断特异性。

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