School of Chemical and Biological Engineering, Institute for Chemical Processing, Seoul National University, 1 Gwanak-gu, Gwanak-ro, Seoul, 151-744, Republic of Korea.
Arch Pharm Res. 2014 Jan;37(1):120-8. doi: 10.1007/s12272-013-0303-3. Epub 2013 Dec 6.
Magnetic nanoparticles have been subjected to extensive studies in the past few decades owing to their promising potentials in biomedical applications. The versatile intrinsic properties of magnetic nanoparticles enable their use in many biomedical applications. Recently, magnetic nanoparticles were utilized to control the cell's function. In addition, intracellular delivery of magnetic nanoparticles allowed cell's positioning by appropriate use of magnetic field and created cellular cluster. Furthermore, magnetic nanoparticles have been utilized to assemble more complex tissue structures than those that are achieved by conventional scaffold-based tissue engineering strategies. This review addresses recent work in the use magnetic nanoparticle for controlled tissue assembly and complex tissue formation.
磁性纳米粒子在过去几十年中受到了广泛的研究，因为它们在生物医学应用中有很大的潜力。磁性纳米粒子的多功能内在特性使其能够应用于许多生物医学应用中。最近，磁性纳米粒子被用于控制细胞的功能。此外，通过适当利用磁场和创建细胞簇，磁性纳米粒子可以实现细胞的定位。此外，磁性纳米粒子已被用于组装比传统支架组织工程策略更复杂的组织结构。本文综述了磁性纳米粒子在控制组织组装和复杂组织形成方面的最新研究进展。
