脊索瘤的临床病理特征：机构经验及文献综述
Clinicopathological characteristics of chordoma: an institutional experience and a review of the literature.
作者信息
Makhdoomi Rumana, Ramzan Altaf, Khursheed Nayil, Bhat Salma, Baba Khalil, Mohsin Rasool, Basharat Mubeen, Yameen Bhat, Ahmad Rayees, Iqbal Lone, Maqbool Mohammad, Ajaz Hakeem, Farhat Mustafa
机构信息
Skims, Department of Pathology, Srinagar, Kashmir, India.
出版信息
Turk Neurosurg. 2013;23(6):700-6. doi: 10.5137/1019-5149.JTN.5941-12.3.
AIM
To study the clinicopathologic characteristics of chordomas from a single institution.
MATERIAL AND METHODS
This study is a retrospective analysis of 18 cases of chordomas diagnosed over a period of 5-years at Sher-i-Kashmir Institute of Medical Sciences, Srinagar, from 2006 to 2010.
RESULTS
The overall mean age of the patients was 46.72 years. Males outnumbered females. Sacrum was the commonest site involved. Histopathologically, the majority of cases were conventional chordoma with four cases of chondroid variety. There was a single case of dedifferentiated chordoma that presented with bone metastasis. Most patients did well after surgery and radiotherapy. One patient had a local recurrence and one patient with dedifferentiated variant died on follow-up.
CONCLUSION
Though locally aggressive, chordomas are effectively treated with resection and postoperative radiotherapy.
目的
研究来自单一机构的脊索瘤的临床病理特征。
材料与方法
本研究是对2006年至2010年期间在斯利那加的谢里-克什米尔医学科学研究所诊断出的18例脊索瘤进行的回顾性分析。
结果
患者的总体平均年龄为46.72岁。男性多于女性。骶骨是最常受累的部位。组织病理学上，大多数病例为传统型脊索瘤，有4例软骨样型。有1例去分化型脊索瘤伴有骨转移。大多数患者术后接受放疗后情况良好。1例患者出现局部复发，1例去分化型患者在随访中死亡。
结论
尽管脊索瘤具有局部侵袭性，但通过手术切除和术后放疗可有效治疗。
Zotero 插件