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松果体产生甲氧基吲哚似乎取决于羟基前体的浓度及其对羟基吲哚 - O - 甲基转移酶的亲和力。

Methoxyindole production by the pineal gland appears to be dependent on the concentration of hydroxy precursors and their affinity for hydroxyindole-O-methyltransferase.

作者信息

Morton D J

出版信息

J Endocrinol. 1986 Oct;111(1):133-6. doi: 10.1677/joe.0.1110133.

DOI:10.1677/joe.0.1110133
PMID:2431088
Abstract

Various pineal gland indole metabolites were separated by thin-layer chromatography after organ culture with tritiated serotonin. The amounts of methoxyindoles produced were remarkably constant and female rats in oestrus appeared to produce greater amounts than male rats. The results show a correlation between methylation and the concentration and affinity of the various hydroxyindoles for hydroxyindole-O-methyltransferase.

摘要

用氚标记的血清素进行器官培养后，通过薄层色谱法分离了各种松果体吲哚代谢物。所产生的甲氧基吲哚的量非常恒定，处于发情期的雌性大鼠产生的量似乎比雄性大鼠更多。结果表明甲基化与各种羟基吲哚对羟基吲哚-O-甲基转移酶的浓度和亲和力之间存在相关性。

相似文献

1
Methoxyindole production by the pineal gland appears to be dependent on the concentration of hydroxy precursors and their affinity for hydroxyindole-O-methyltransferase.松果体产生甲氧基吲哚似乎取决于羟基前体的浓度及其对羟基吲哚 - O - 甲基转移酶的亲和力。
J Endocrinol. 1986 Oct;111(1):133-6. doi: 10.1677/joe.0.1110133.
2
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