10日龄大鼠松果体中5-羟吲哚和去甲肾上腺素甲基化的昼夜节律性。
Circadian rhythmicity in the methylation of 5-hydroxyindoles and norepinephrine in the pineal gland of 10 day old rats.
作者信息
Balemans M G, Bary F A, Legerstee W C, Noordegraaf E M
出版信息
J Neural Transm. 1978;43(2):167-75. doi: 10.1007/BF01579076.
PMID:310446
Abstract
In pineals of 10 day old rats 5-hydroxytryptophan, 5-hydroxyindole-3-acetic acid, N-acetylserotonin/5-hydroxytryptophol and norepinephrine are methylated following a circadian rhythm. During the night HIOMT and COMT activities were measured for the above mentioned substrates, while HIOMT activity for 5-hydroxytryptophan and N-acetylserotonin/5-hydroxytryptophol was also determined during daytime.
摘要
在10日龄大鼠的松果体中，5-羟色氨酸、5-羟吲哚-3-乙酸、N-乙酰血清素/5-羟色醇和去甲肾上腺素按照昼夜节律进行甲基化。夜间测定上述底物的羟基吲哚-O-甲基转移酶（HIOMT）和儿茶酚-O-甲基转移酶（COMT）活性，同时也在白天测定5-羟色氨酸和N-乙酰血清素/5-羟色醇的HIOMT活性。
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