Richard Patrick, Ordonez Nydia Icaza, Tu Le Mai
Department of Urology, Sherbrooke University, Québec, Canada.
Urol Ann. 2013 Oct;5(4):264-8. doi: 10.4103/0974-7796.120303.
The pressure-flow study (PFS) is considered the gold standard for the detection of bladder outlet obstruction (BOO) in men. However, several studies have raised the possibility that transurethral catheterization might have an obstructive effect on PFS while others did not.
To evaluate the effect of a 6 Fr transurethral catheter on the pressure-flow study and to evaluate its clinical implication in men.
A retrospective chart review study of 515 men referred for an evaluation of lower urinary tract symptoms and who underwent an urodynamic study (UDS). Of those, 133 met our inclusion/exclusion criteria. Non invasive free-flow studies (NIFFS) were performed before every UDS. Cystometrogram and PFS were performed through a 6 Fr transurethral catheter.
The maximal flow rate (Qmax) was significantly higher (P < 0.001) in the NIFFS (15.0 mL/s (range 9.0-23.0)) than in the PFS (11.0 mL/s (range 7.0-18.5)). This difference became greater (18.5 mL/s (range 10.0-30.3) vs. 13.0 mL/s (range 6.0-25.0), in favor of the NIFFS) when we analyzed only the patients (n = 34) who voided a similar volume. According to the International Continence Society (ICS) nomogram, the use of the PFS alone would have resulted in the upstaging of 14% of cases (10/71) in the overall population and 24% (4/17) in the sub-analyzed group.
A 6 Fr transurethral catheter significantly lowers the maximal flow rate by 4 mL/s. Its presence resulted in an upstaging on the ICS nomogram. However, further studies will be necessary to confirm this upstaging.
压力-流率研究(PFS)被认为是男性膀胱出口梗阻(BOO)检测的金标准。然而,一些研究提出经尿道插管可能对PFS产生梗阻作用,而其他研究则未发现此现象。
评估6F经尿道导管对压力-流率研究的影响,并评估其在男性中的临床意义。
对515名因下尿路症状接受评估并进行尿动力学研究(UDS)的男性进行回顾性图表审查研究。其中,133名符合纳入/排除标准。在每次UDS前进行无创自由流率研究(NIFFS)。通过6F经尿道导管进行膀胱测压和PFS。
NIFFS中的最大尿流率(Qmax)(15.0 mL/s(范围9.0 - 23.0))显著高于PFS中的最大尿流率(11.0 mL/s(范围7.0 - 18.5))(P < 0.001)。当我们仅分析排尿量相似的患者(n = 34)时,这种差异变得更大(分别为18.5 mL/s(范围10.0 - 30.3)和13.0 mL/s(范围6.0 - 25.0),NIFFS更优)。根据国际尿控协会(ICS)列线图,仅使用PFS会导致总体人群中14%(10/71)的病例分期上调,在亚分析组中为24%(4/17)。
6F经尿道导管使最大尿流率显著降低4 mL/s。其存在导致ICS列线图分期上调。然而,需要进一步研究来证实这种分期上调。