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癌胚蛋白和激素作为肿瘤标志物的临床应用。

Clinical utility of oncofetal proteins and hormones as tumor markers.

作者信息

Garrett P E, Kurtz S R

出版信息

Med Clin North Am. 1986 Nov;70(6):1295-306. doi: 10.1016/s0025-7125(16)30899-9.

DOI:10.1016/s0025-7125(16)30899-9
PMID:2431237
Abstract

This article reviews the two most common hormones that act as tumor markers, human chorionic gonadotropin (HCG) and prolactin, and the two most common oncofetal proteins, carcinoembryonic antigen (CEA) and alpha-feto-protein (AFP). Assays for these markers are discussed in terms of their methodologies and performance in the clinical setting.

摘要

本文综述了两种最常见的作为肿瘤标志物的激素,即人绒毛膜促性腺激素(HCG)和催乳素,以及两种最常见的癌胚蛋白,即癌胚抗原(CEA)和甲胎蛋白(AFP)。本文从这些标志物检测方法及其在临床环境中的表现方面进行了讨论。

相似文献

1
Clinical utility of oncofetal proteins and hormones as tumor markers.癌胚蛋白和激素作为肿瘤标志物的临床应用。
Med Clin North Am. 1986 Nov;70(6):1295-306. doi: 10.1016/s0025-7125(16)30899-9.
2
[Serum markers in malignant diseases].[恶性疾病中的血清标志物]
Med Lab (Stuttg). 1981 Nov;34(11):262-71.
3
[Studies on the tumor markers in the germinal testicular tumors. Cellular localization of alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG) and carcinoembryonic antigen (CEA) in germinal testicular tumors using an indirect immunoperoxidase method].[睾丸生殖细胞肿瘤中肿瘤标志物的研究。采用间接免疫过氧化物酶法对睾丸生殖细胞肿瘤中甲胎蛋白(AFP)、人绒毛膜促性腺激素(HCG)和癌胚抗原(CEA)进行细胞定位]
Nihon Hinyokika Gakkai Zasshi. 1984 Mar;75(3):503-22.
4
A primary lung carcinoma producing alpha-fetoprotein, carcinoembryonic antigen, and human chorionic gonadotropin. Immunohistochemical and biochemical studies.产生甲胎蛋白、癌胚抗原和人绒毛膜促性腺激素的原发性肺癌。免疫组织化学和生化研究。
Cancer. 1987 Dec 1;60(11):2744-50. doi: 10.1002/1097-0142(19871201)60:11<2744::aid-cncr2820601126>3.0.co;2-h.
5
alpha-Fetoprotein (AFP), human chorionic gonadotropin (HCG), and carcinoembryonic antigen (CEA) demonstrated in the immature glands of mediastinal teratocarcinoma: a case report.α-甲胎蛋白(AFP)、人绒毛膜促性腺激素(HCG)和癌胚抗原(CEA)在纵隔畸胎癌未成熟腺体中的表现:一例报告
Cancer. 1982 Sep 15;50(6):1160-5. doi: 10.1002/1097-0142(19820915)50:6<1160::aid-cncr2820500621>3.0.co;2-5.
6
Immunocytochemical evaluation of human esophageal neoplasms and preneoplastic lesions for beta-chorionic gonadotropin, placental lactogen, alpha-fetoprotein, carcinoembryonic antigen, and nonspecific cross-reacting antigen.对人食管肿瘤及癌前病变进行β-绒毛膜促性腺激素、胎盘催乳素、甲胎蛋白、癌胚抗原和非特异性交叉反应抗原的免疫细胞化学评估。
Cancer Res. 1986 Jun;46(6):2936-43.
7
[Cellular localization of alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and carcinoembryonic antigen (CEA) in malignant germ cell tumors of the ovary using immunoperoxidase technique (author's transl)].运用免疫过氧化物酶技术对卵巢恶性生殖细胞肿瘤中甲胎蛋白(AFP)、人绒毛膜促性腺激素(HCG)及癌胚抗原(CEA)进行细胞定位(作者译)
Nihon Sanka Fujinka Gakkai Zasshi. 1980 Jun;32(6):757-66.
8
Immunocytochemical localization of carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), and human chorionic gonadotropin (HCG) in cervical neoplasia.癌胚抗原(CEA)、甲胎蛋白(AFP)和人绒毛膜促性腺激素(HCG)在宫颈肿瘤中的免疫细胞化学定位。
Am J Clin Pathol. 1983 Apr;79(4):414-20. doi: 10.1093/ajcp/79.4.414.
9
Serum tumor markers.血清肿瘤标志物。
Mayo Clin Proc. 1982 Feb;57(2):129-32.
10
Tumor-associated antigen levels (carcinoembryonic antigen, human chorionic gonadotropin, and alpha-fetoprotein) antedating the diagnosis of cancer in the Framingham study.在弗雷明汉研究中,早于癌症诊断的肿瘤相关抗原水平(癌胚抗原、人绒毛膜促性腺激素和甲胎蛋白)。
J Natl Cancer Inst. 1977 Jun;58(6):1547-51. doi: 10.1093/jnci/58.6.1547.

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Biliary glycoprotein is overexpressed in human colon cancer cells with high metastatic potential.胆汁糖蛋白在具有高转移潜能的人结肠癌细胞中过表达。
J Gastrointest Surg. 1997 May-Jun;1(3):292-8. doi: 10.1016/s1091-255x(97)80123-0.
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Detection of malignancy-associated metabolites in the sera of cancer patients by electron capture gas chromatography.通过电子捕获气相色谱法检测癌症患者血清中与恶性肿瘤相关的代谢物。
Br J Cancer. 1994 Apr;69(4):655-62. doi: 10.1038/bjc.1994.127.
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Augmentation of carcinoembryonic antigen release from intact, viable tumor cells by a factor in human serum.人血清中的一种因子增强完整活肿瘤细胞中癌胚抗原的释放。
Ann Surg Oncol. 1995 Jul;2(4):336-42. doi: 10.1007/BF02307067.