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牛至叶:广泛的生药学和植物化学质量评估。

Oreganum vulgare Linn. leaf: An Extensive Pharmacognostical and Phytochemical Quality Assessment.

作者信息

Bharti Veni, Vasudeva Neeru

机构信息

Department of Pharmaceutical Sciences, Guru Jambheshwer University of Science and Technology, Hisar, Haryana, India.

出版信息

Adv Pharm Bull. 2013;3(2):277-81. doi: 10.5681/apb.2013.045. Epub 2013 Aug 20.

Abstract

PURPOSE

Standardization and detailed pharmacognostical studies of Oreganum vulgare Linn. leaf for authentication and commercial utilization.

METHODS

Oreganum vulgare Linn. leaf was with standardization according to standard procedures described in WHO, 2011 and I.P. 1996.

RESULTS

The physicochemical parameters total ash, acid insoluble ash, water soluble ash and sulphated ash were found to be 11.5%, 11%, 5, 10.5% w/w respectively. Foaming index was found be <100. The trace elements were found to be copper, lead, cadmium, zinc, cobalt, manganese, nickel and copper in ethanol extract and phytochemical screening of aqueous and ethanol extract showed the presence of carbohydrates, flavonoids, anthocyanins, phenolic compounds etc.

CONCLUSION

The standardization parameters viz. physico-chemical parameters, macroscopy, microscopy, taxonomy, anatomy and preliminary phytochemical screening, microbial and aflatoxin count, HPTLC profile is being reported to help in authentication and development of monograph of this plant.

摘要

目的

对牛至叶进行标准化及详细的生药学研究,以用于鉴定和商业利用。

方法

按照世界卫生组织2011年及印度药典1996年所述的标准程序对牛至叶进行标准化。

结果

发现其物理化学参数,即总灰分、酸不溶性灰分、水溶性灰分和硫酸化灰分分别为11.5%、11%、5%、10.5%(w/w)。发泡指数<100。在乙醇提取物中发现的微量元素有铜、铅、镉、锌、钴、锰、镍和铜,对水提取物和乙醇提取物的植物化学筛选表明存在碳水化合物、黄酮类化合物、花青素、酚类化合物等。

结论

报告了标准化参数,即物理化学参数、宏观特征、微观特征、分类学、解剖学和初步植物化学筛选、微生物和黄曲霉毒素计数、高效薄层色谱图谱,以帮助鉴定和制定该植物的专著。

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