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苏丹喀土穆州孕妇风疹抗体阳性率。

Seroprevalence of rubella among pregnant women in Khartoum state, Sudan.

机构信息

Department of Medical Biotechnology, Commission for Biotechnology and Genetic Engineering, National Centre for Research, Khartoum, Sudan.

出版信息

East Mediterr Health J. 2013 Sep;19(9):812-5.

Abstract

Rubella vaccine is not included in the Sudanese national immunization programme, and data on prevalence of rubella among women of childbearing age are inadequate. The objective of this cross-sectional study was to determine the seroprevalence of rubella among pregnant women in Khartoum state, Sudan. A total of 500 pregnant women who visited 7 antenatal clinics from November 2008 to March 2009 were examined for the presence of rubella IgG antibodies using ELISA. Rubella IgG antibodies were detected in 95.1% (95% Cl: 93.2%-97.0%) of women. This seroprevalence was significantly associated with education level, but not with age, residence area, occupation or parity. We presume this high seroprevalence indicates a high circulation of wild rubella virus in Khartoum state. Similar studies in other Sudanese states would be important for informing a decision to introduce rubella vaccine to Sudan.

摘要

风疹疫苗不在苏丹国家免疫计划中,有关育龄妇女风疹流行情况的数据也不足。本横断面研究的目的是确定苏丹喀土穆州孕妇的风疹血清流行率。2008 年 11 月至 2009 年 3 月,共有 500 名孕妇在 7 个产前诊所接受了酶联免疫吸附试验检测风疹 IgG 抗体。95.1%(95%可信区间:93.2%-97.0%)的女性检测出风疹 IgG 抗体。这种血清流行率与教育程度显著相关,但与年龄、居住地区、职业或产次无关。我们推测这种高血清流行率表明野生风疹病毒在喀土穆州的传播较为活跃。在其他苏丹州开展类似研究,对于决定向苏丹引入风疹疫苗非常重要。

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