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腰椎退行性后凸手术治疗后近端交界性后凸进展的发生率及危险因素分析:至少2年随访

Analysis of the incidence and risk factors for the progression of proximal junctional kyphosis following surgical treatment for lumbar degenerative kyphosis: minimum 2-year follow-up.

作者信息

Lee Jung-Hoon, Kim Jin-Uk, Jang Jee-Soo, Lee Sang-Ho

机构信息

Department of Neurosurgery, Suwon Nanoori Hospital , Gyunggi Province , Korea.

出版信息

Br J Neurosurg. 2014 Apr;28(2):252-8. doi: 10.3109/02688697.2013.835369. Epub 2013 Dec 9.

DOI:10.3109/02688697.2013.835369
PMID:24313308
Abstract

BACKGROUND CONTEXT. Proximal junctional kyphosis (PJK) following surgical treatment of lumbar degenerative kyphosis (LDK) is one of the critical complications leading to the failure of instrumentation and additional extensive surgery. However, most previous studies have focused on idiopathic scoliosis resulting from variable surgical techniques. LDK usually differ from other scoliotic deformities in terms of patient characteristics and disease mechanisms. PURPOSE. Identification of the prevalence of PJK after the surgical treatment of LDK and searching for the predictable value for the progression of PJK. Study design. Retrospective comparative study. Patient sample (must be included in clinical studies). Forty-seven consecutive patients who underwent surgical correction of a sagittal imbalance due to LDK, from January 2005 to December 2008 in a single spine clinic, were evaluated with a minimum 2 years follow-up (mean 3.8 years). METHODS. Patients were divided into 2 groups: with or without the occurrence of PJK, and three categorized factors according to patient characteristics, surgical variables, and the radiographic spinopelvic parameters were evaluated. RESULTS. PJK had occurred in 29 of 47 patients (61.7%). Among variable factors, old age, upper-instrumented vertebra below L2, lumbar lordosis to PI ratio, and the sum of lumbar lordosis, and the sacral slope related to PI were found to be statistically significant. CONCLUSIONS. The overall incidence of PJK following surgical treatment of LDK patients was higher than expected. Spinal biomechanics may be changed after long instrumented fusion surgery. Thorough consideration of these factors is needed in the treatment strategy of LDK patients. A long-term follow-up study should be conducted.

摘要

背景

腰椎退行性后凸畸形(LDK)手术治疗后近端交界性后凸(PJK)是导致内固定失败及需要再次进行广泛手术的关键并发症之一。然而,既往大多数研究聚焦于因手术技术不同导致的特发性脊柱侧凸。LDK在患者特征和疾病机制方面通常与其他脊柱侧凸畸形不同。

目的

确定LDK手术治疗后PJK的发生率,并寻找PJK进展的预测指标。

研究设计

回顾性对照研究。

患者样本(必须纳入临床研究):2005年1月至2008年12月在一家脊柱诊所连续接受手术矫正因LDK导致矢状面失衡的47例患者,进行了至少2年的随访(平均3.8年)。

方法

将患者分为两组:发生PJK组和未发生PJK组,并对根据患者特征、手术变量及影像学脊柱骨盆参数划分的三个类别因素进行评估。

结果

47例患者中有29例(61.7%)发生了PJK。在各种可变因素中,高龄、L2以下上固定椎、腰椎前凸与骨盆入射角(PI)比值、腰椎前凸总和以及与PI相关的骶骨倾斜度具有统计学意义。

结论

LDK患者手术治疗后PJK的总体发生率高于预期。长期内固定融合手术后脊柱生物力学可能发生改变。在LDK患者的治疗策略中需要充分考虑这些因素。应进行长期随访研究。

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