Adamczyk A, Fiszer M, Kaciński M, Wyszkowski J
Neurol Neurochir Pol. 1986 May-Jun;20(3):222-7.
In the cerebrospinal fluid of 26 children with SSPE the levels of prealbumins and total proteins were determined and electrophoretic separation of proteins was done. The usefulness is discussed of the percent proportion of prealbumins in the cerebrospinal fluid as a criterion indicating damage to the blood-cerebrospinal fluid barrier with increased penetration of proteins in SSPE. It is concluded that in diseases in which biosynthesis occurs of proteins in the central nervous system the percent proportion of prealbumins fails to reflect the integrity of the brain-cerebrospinal fluid barrier.
对26例亚急性硬化性全脑炎(SSPE)患儿的脑脊液进行了前清蛋白和总蛋白水平测定,并对蛋白质进行了电泳分离。讨论了脑脊液中前清蛋白的百分比作为一种标准的实用性,该标准可指示在SSPE中血脑脊髓液屏障受损且蛋白质渗透增加的情况。得出的结论是,在中枢神经系统中发生蛋白质生物合成的疾病中,前清蛋白的百分比不能反映脑-脑脊液屏障的完整性。