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两种妊娠队列的样本特征比较:基于社区与基于人群的招募方法。

Comparison of sample characteristics in two pregnancy cohorts: community-based versus population-based recruitment methods.

机构信息

Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada.

出版信息

BMC Med Res Methodol. 2013 Dec 6;13:149. doi: 10.1186/1471-2288-13-149.

Abstract

BACKGROUND

One of the biggest challenges for population health studies is the recruitment of participants. Questions that investigators have asked are "who volunteers for studies?" and "does recruitment method influence characteristics of the samples?" The purpose of this paper was to compare sample characteristics of two unrelated pregnancy cohort studies taking place in the same city, in the same time period, that employed different recruitment strategies, as well as to compare the characteristics of both cohorts to provincial and national statistics derived from the Maternity Experiences Survey (MES).

METHODS

One pregnancy cohort used community-based recruitment (e.g. posters, pamphlets, interviews with community media and face-to-face recruitment in maternity clinics); the second pregnancy cohort used both community-based and population-based (a centralized system identifying pregnant women undergoing routine laboratory testing) strategies.

RESULTS

The pregnancy cohorts differed in education, income, ethnicity, and foreign-born status (p < 0.01), but were similar for maternal age, BMI, and marital status. Compared to the MES, the lowest age, education, and income groups were under-represented, and the cohorts were more likely to be primiparous.

CONCLUSIONS

The findings suggest that non-stratified strategies for recruitment of participants will not necessarily result in samples that reflect the general population, but can reflect the target population of interest. Attracting and retaining young, low resource women into urban studies about pregnancy may require alternate and innovative approaches.

摘要

背景

人群健康研究面临的最大挑战之一是参与者的招募。研究人员提出的问题是“谁自愿参加研究?”以及“招募方法是否会影响样本特征?”本文的目的是比较在同一城市、同一时期进行的两项无关妊娠队列研究的样本特征,这两项研究采用了不同的招募策略,并将这两个队列的特征与省级和国家级统计数据(来自孕产妇经历调查)进行比较。

方法

一个妊娠队列使用基于社区的招募方法(例如海报、小册子、与社区媒体的访谈以及在妇产科诊所的面对面招募);第二个妊娠队列使用基于社区和基于人群的策略(一个集中系统确定正在进行常规实验室检查的孕妇)。

结果

妊娠队列在教育程度、收入、种族和外国出生状况方面存在差异(p<0.01),但在母亲年龄、BMI 和婚姻状况方面相似。与 MES 相比,年龄、教育程度和收入最低的群体代表性不足,队列中初次生育的比例更高。

结论

研究结果表明,非分层的参与者招募策略不一定会导致反映总体人群的样本,但可以反映感兴趣的目标人群。吸引和留住年轻、资源匮乏的城市孕妇参加关于妊娠的研究可能需要替代和创新的方法。

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