Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan.
BMC Gastroenterol. 2013 Dec 6;13:166. doi: 10.1186/1471-230X-13-166.
The incidence of the inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's disease (CD), has been increasing in Asia. We probed the nationwide registered database to assess the incidence, prevalence, gender distribution, age of diagnosis and the survival status of IBD patients in Taiwan.
A retrospective study was conducted to analyze the registered database compiled by the National Health Insurance provided by the Department of Health, Taiwan, from January 1998 through December 2008.
A total of 1591 IBD patients were registered from 1998 to 2008 in Taiwan (CD: 385; UC: 1206). The incidence of CD increased from 0.19/100,000 in 1998 to 0.24/100,000 in 2008. The incidence of UC increased from 0.61/100,000 in 1998 to 0.94/100,000 in 2008. The prevalence of CD increased from 0.19/100,000 in 1998 to 1.78/100,000 in 2008. The prevalence of UC increased from 0.61/100,000 in 1998 to 7.62/100,000 in 2008. Male to female ratio for CD was 2.22 and 1.64 for UC. Age of registered for CD was predominantly between 20 to 39, and for UC between 30 to 49 years of age. The standardized mortality ratio (95% CI) was 4.97 (3.72-6.63) for CD and 1.78 (1.46-2.17) for UC, from 1998 to 2008 in Taiwan.
Using the Taiwan nationwide database for IBD, the incidence and prevalence of IBD in Taiwan significantly increased from 1998 to 2008. The mortality rate was higher for CD patients than UC patients, and both were higher than the general population.
炎症性肠病（IBD）、溃疡性结肠炎（UC）和克罗恩病（CD）的发病率在亚洲不断上升。我们利用全国性的注册数据库来评估台湾 IBD 患者的发病率、患病率、性别分布、诊断年龄和生存状况。
我们对台湾卫生署提供的国家健康保险所编纂的注册数据库进行了回顾性研究，该数据库涵盖了 1998 年 1 月至 2008 年 12 月的数据。
在台湾，1998 年至 2008 年共登记了 1591 例 IBD 患者（CD：385；UC：1206）。CD 的发病率从 1998 年的 0.19/100000 上升到 2008 年的 0.24/100000。UC 的发病率从 1998 年的 0.61/100000 上升到 2008 年的 0.94/100000。CD 的患病率从 1998 年的 0.19/100000 上升到 2008 年的 1.78/100000。UC 的患病率从 1998 年的 0.61/100000 上升到 2008 年的 7.62/100000。CD 患者的男女比例为 2.22，UC 患者的男女比例为 1.64。CD 的登记年龄主要在 20 至 39 岁之间，UC 的登记年龄主要在 30 至 49 岁之间。1998 年至 2008 年，台湾 CD 的标准化死亡率（95%CI）为 4.97（3.72-6.63），UC 的标准化死亡率为 1.78（1.46-2.17）。
利用台湾全国性的 IBD 数据库，台湾 IBD 的发病率和患病率从 1998 年到 2008 年显著增加。CD 患者的死亡率高于 UC 患者，且均高于一般人群。
