来自 Jaborosa caulescens var. bipinnatifida 的醉茄内酯。
Withanolides from Jaborosa caulescens var. bipinnatifida.
机构信息
Department of Medicinal Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS 66045, USA.
The Small-Molecule X-ray Crystallography Laboratory, University of Kansas, Lawrence, KS 66047, USA.
出版信息
Phytochemistry. 2014 Feb;98:232-5. doi: 10.1016/j.phytochem.2013.11.005. Epub 2013 Dec 5.
Abstract
Withanolides 2,3-dihydrotrechonolide A (1) and 2,3-dihydro-21-hydroxytrechonolide A (2) were isolated along with two known withanolides trechonolide A (3) and jaborosalactone 39 (4) from Jaborosa caulescens var. bipinnatifida (Solanaceae). The structures of 1-2 were elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure of withanolide 1 was confirmed by X-ray crystallographic analysis.
摘要
从长柄茄 Jaborosa caulescens var. bipinnatifida（茄科）中分离得到了两种新的 2,3-二氢特雷醇内酯类化合物 2,3-二氢特雷醇内酯 A（1）和 2,3-二氢-21-羟基特雷醇内酯 A（2），以及两种已知的特雷醇内酯类化合物特雷醇内酯 A（3）和 jaborosalactone 39（4）。通过二维 NMR 和其他光谱技术阐明了 1-2 的结构。此外，通过 X 射线晶体学分析确定了 1 的结构。
相似文献
1
Withanolides from Jaborosa caulescens var. bipinnatifida.来自 Jaborosa caulescens var. bipinnatifida 的醉茄内酯。
Phytochemistry. 2014 Feb;98:232-5. doi: 10.1016/j.phytochem.2013.11.005. Epub 2013 Dec 5.
2
Withanolides with phytotoxic activity from Jaborosa caulescens var. caulescens and J. caulescens var. bipinnatifida 1.来自多茎刺茄变种多茎刺茄和多茎刺茄变种二回羽状裂叶刺茄的具有植物毒性活性的睡茄内酯1 。
J Nat Prod. 2007 May;70(5):808-12. doi: 10.1021/np070030g. Epub 2007 Apr 12.
3
Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations.来自卡氏蒟蒻薯和反射蒟蒻薯的醉茄内酯衍生物的抗增殖活性。化学分类学的考虑。
Phytochemistry. 2012 Apr;76:150-7. doi: 10.1016/j.phytochem.2011.12.018. Epub 2012 Feb 8.
4
Withanolides from Jaborosa laciniata.来自裂叶刺茄的睡茄内酯类化合物。
J Nat Prod. 2007 Oct;70(10):1644-6. doi: 10.1021/np070197+. Epub 2007 Sep 21.
5
Phytotoxic withanolides from Jaborosa rotacea.来自圆叶刺茄的具有植物毒性的睡茄内酯
J Nat Prod. 2006 May;69(5):783-9. doi: 10.1021/np0600090.
6
Withanolides from Jaborosa kurtzii.来自库氏刺茄的睡茄内酯
J Nat Prod. 2007 Sep;70(9):1513-5. doi: 10.1021/np0701780. Epub 2007 Aug 22.
7
Antiproliferative withanolides from several solanaceous species.几种茄科植物中的抗增殖醉茄内酯。
Nat Prod Res. 2014;28(22):1941-51. doi: 10.1080/14786419.2014.919286. Epub 2014 May 28.
8
Withanolides from Physalis coztomatl.酸浆（Physalis coztomatl）中的睡茄内酯类化合物
Phytochemistry. 2015 Jan;109:147-53. doi: 10.1016/j.phytochem.2014.10.012. Epub 2014 Nov 8.
9
Withanolide Profile and Acetylcholinesterase Inhibitory Activity of Two Argentinean Jaborosa Species.两种阿根廷 Jaborosa 物种的醉茄内酯成分分析和乙酰胆碱酯酶抑制活性。
Planta Med. 2024 Jun;90(7-08):561-575. doi: 10.1055/a-2255-7096. Epub 2024 Jun 6.
10
Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations.来自茄科德普雷亚属三个物种的睡茄内酯。化学分类学考量。
Phytochemistry. 2015 Feb;110:83-90. doi: 10.1016/j.phytochem.2014.11.015. Epub 2014 Nov 27.
引用本文的文献
1
Antiproliferative withanolides from several solanaceous species.几种茄科植物中的抗增殖醉茄内酯。
Nat Prod Res. 2014;28(22):1941-51. doi: 10.1080/14786419.2014.919286. Epub 2014 May 28.
本文引用的文献
1
Anti-proliferative withanolides from the Solanaceae: a structure-activity study.茄科植物中具有抗增殖活性的睡茄内酯：结构-活性研究
Pure Appl Chem. 2012;84(6):1353-1367. doi: 10.1351/PAC-CON-11-10-08.
2
Antiproliferative withanolides from Datura wrightii.来自曼陀罗的具有抗增殖作用的醉茄内酯。
J Nat Prod. 2013 Mar 22;76(3):445-9. doi: 10.1021/np300766p. Epub 2012 Dec 19.
3
Minor withanolides of Physalis longifolia: structure and cytotoxicity.酸浆小叶中的次要睡茄内酯：结构与细胞毒性。
Chem Pharm Bull (Tokyo). 2012;60(10):1234-9. doi: 10.1248/cpb.c12-00305.
4
Chlorinated Withanolides from Withania somnifera.来自印度人参的氯化睡茄内酯
Phytochem Lett. 2011 Dec;4(4):411-414. doi: 10.1016/j.phytol.2011.04.016.
5
Cytotoxic withanolide constituents of Physalis longifolia.具有细胞毒性的长梗酸浆化学成分。
J Nat Prod. 2011 Dec 27;74(12):2532-44. doi: 10.1021/np200635r. Epub 2011 Nov 18.
6
Withanolides and related steroids.睡茄内酯及相关甾体化合物。
Prog Chem Org Nat Prod. 2011;94:127-229. doi: 10.1007/978-3-7091-0748-5_3.
7
Natural withanolides: an overview.天然醉茄内酯：概述。
Nat Prod Rep. 2011 Apr;28(4):705-40. doi: 10.1039/c0np00045k. Epub 2011 Feb 23.
8
Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.维甲酰新苦木内酯 A，一种来自短梗苦木的细胞毒甾体，诱导人头颈鳞癌细胞凋亡。
J Nat Prod. 2010 Sep 24;73(9):1476-81. doi: 10.1021/np100112p.
9
Withanolides with phytotoxic activity from Jaborosa caulescens var. caulescens and J. caulescens var. bipinnatifida 1.来自多茎刺茄变种多茎刺茄和多茎刺茄变种二回羽状裂叶刺茄的具有植物毒性活性的睡茄内酯1 。
J Nat Prod. 2007 May;70(5):808-12. doi: 10.1021/np070030g. Epub 2007 Apr 12.
10
Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora.
J Nat Prod. 2003 Aug;66(8):1089-93. doi: 10.1021/np030081n.
Zotero 插件