Jibbe A, Tefft K, Weir G, Aires D, Liu D
University of Kansas School of Medicine.
Dermatol Online J. 2013 Nov 15;19(11):20396.
Drug-induced erythema in the distribution of prior sunburn is called photo recall. Although more commonly induced by chemotherapeutics, it has also been associated with antibiotics such as ampicillin, cephalosporin, and gentamicin. Vancomycin has not been previously reported as a causal agent. This case report describes photo recall in a fifty-three year old woman undergoing treatment with vancomycin for a MRSA infection of the spine. Her eruption followed a photo-distributed pattern on the chest, shoulders, neck and face sparing areas previously protected by her bathing suit. Of note, she reported a similar eruption following vancomycin two years prior.
药物引起的、出现在既往晒伤部位的红斑称为光召回反应。虽然更常见于由化疗药物诱发,但也与氨苄西林、头孢菌素和庆大霉素等抗生素有关。此前尚未有万古霉素作为致病因素的报道。本病例报告描述了一名53岁女性在接受万古霉素治疗脊柱耐甲氧西林金黄色葡萄球菌感染时出现的光召回反应。她的皮疹呈光分布模式,出现在胸部、肩部、颈部和面部,避开了之前泳衣覆盖的部位。值得注意的是,她报告两年前使用万古霉素后也曾出现类似皮疹。