Domínguez J, Harrison R, Atal R, Larraín L
Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Transplant Proc. 2013;45(10):3711-5. doi: 10.1016/j.transproceed.2013.08.077.
In this article we present an economic evaluation of policies aimed at increasing deceased organ donation in Chile, a developing country that has low donation rates; it had 5.4 donors per million people (pmp) in 2010.
Expert opinions of leading participants in donation and transplantation were analyzed, resulting in a set of local policies aimed at increasing donation rates. Using previous results of reported cost savings of increasing kidney transplantation in Chile, we estimated the net benefits of these policies, as a function of additional donors.
The main problem of the Chilean system seems to be the low capability to identify potential donors and a deficit in intensive care unit (ICU) beds. Among considered policies central to increase donation are the following: increasing human and capital resources dedicated to identifying potential donors, providing ICU beds from private centers, and developing an online information system that facilitates procurement coordination and the evaluation of performance at each hospital. Our results show that there is a linear relationship between cost savings and incremental donors pmp. For example, if these policies are capable of elevating donation rates in Chile by 6 donors pmp net estimated cost savings are approximately US $1.9 million. Likewise, considering the effect on patients' quality of life, savings would amount to around $15.0 million dollars per year.
Our estimates suggest that these policies have a large cost-saving potential. In fact, considering implementation costs, cost reduction is positive after 4 additional donors pmp, and increasing afterward.
在本文中,我们对旨在提高智利遗体器官捐赠率的政策进行了经济评估。智利是一个捐赠率较低的发展中国家,2010年每百万人口中有5.4名捐赠者。
分析了捐赠和移植领域主要参与者的专家意见,得出了一系列旨在提高捐赠率的地方政策。利用智利此前报告的增加肾移植节省成本的结果,我们估计了这些政策的净效益,这是额外捐赠者数量的函数。
智利系统的主要问题似乎是识别潜在捐赠者的能力较低以及重症监护病房(ICU)床位不足。在考虑的提高捐赠率的核心政策中,包括以下几点:增加用于识别潜在捐赠者的人力和资金资源,从私立中心提供ICU床位,以及开发一个在线信息系统,以促进采购协调和对每家医院的绩效评估。我们的结果表明,节省成本与每百万人口中新增捐赠者数量之间存在线性关系。例如,如果这些政策能够将智利的捐赠率提高每百万人口6名捐赠者,估计净节省成本约为190万美元。同样,考虑到对患者生活质量的影响,每年节省的费用约为1500万美元。
我们的估计表明,这些政策具有很大的节省成本潜力。事实上,考虑到实施成本,在每百万人口新增4名捐赠者之后成本降低为正,且之后还会增加。