Percutaneous interventional therapies for the treatment of patients with severe pulmonary hypertension.

Despite improvements in medical therapy, the overall prognosis of patients with severe pulmonary arterial hypertension remains poor. Heart-lung transplantation or bilateral lung transplantation is the final pathway for a minority. This paper describes both established and novel percutaneous interventional techniques that may palliate or bridge pulmonary hypertension patients to transplantation.