Department of Surgery, Faculty of Health Sciences, University of Buea, PO Box 126, Limbe, Cameroon.
Int J Surg. 2014;12(2):113-9. doi: 10.1016/j.ijsu.2013.11.017. Epub 2013 Dec 3.
Splenectomy is a powerful therapeutic procedure in a wide variety of medical disorders provided that it is not undertaken lightly and the risks are weighed against the potential benefits in each individual case. Most of this risk seems to be due to the underlying splenectomy indication and not to splenectomy alone. There has been an increased tendency in recent years towards splenic preservation to prevent not only the risk of subsequent overwhelming post-splenectomy infection (OPSI) but the long term risk of cardiovascular complications. As there is no condition that can be cured by splenectomy, this paper reviewed the rationale behind the indications for, and the associated risks.
Electronic searches of the medline (PubMed) database, Cochrane library, and science citation index were performed to identify original published studies on splenectomy. Relevant articles were searched from relevant chapters in specialized texts and all included.
目的：阐明脾切除术在多种医学疾病中是一种强有力的治疗手段，但不能轻易进行，应权衡每种情况下的潜在益处和风险。大多数风险似乎归因于潜在的脾切除术适应证，而不仅仅是脾切除术本身。近年来，为了预防继发性感染性全身并发症（OPSI）和长期心血管并发症，人们越来越倾向于保留脾脏。由于没有哪种疾病可以通过脾切除术治愈，因此本文回顾了脾切除术适应证及其相关风险的理论依据。
方法：通过电子检索 medline（PubMed）数据库、 Cochrane 图书馆和科学引文索引，查找有关脾切除术的原始研究。从专业教材的相关章节中搜索相关文章并全部纳入。
