Yan Shuai, Wang Zihan, Lu Jiajie, Yuan Liuxia, Ju Linling, Wang Huixuan, Chen Lin, Cai Weihua, Xiao Feng, Wu Jinzhu
Medical School of Nantong University, Nantong University, Nantong, Jiangsu, China.
Institute of Liver Diseases, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.
Front Immunol. 2025 Jul 28;16:1530363. doi: 10.3389/fimmu.2025.1530363. eCollection 2025.
Sclerosing angiomatoid nodular transformation (SANT)is a rare vascular sclerosing mass-like lesion, often discovered incidentally during routine imaging evaluation or during visits for the patient's primary disease. SANT has complex pathological manifestations, unknown natural course of development and rarity, which makes it difficult for clinicians and pathologists to define its true nature. We report a 55-year-old male patient who came to see a doctor due to a physical examination accidentally found a spleen mass. He had hypertension and hyperlipidemia, and had no obvious clinical symptoms. After that, he underwent surgical resection of the spleen, and the patient had no special discomfort after treatment. Our results show that surgical resection is an efficient treatment for SANT patients without obvious clinical symptoms, but the patient 's comprehensive conditions should also be considered.
硬化性血管瘤样结节性转化（SANT）是一种罕见的血管硬化性肿块样病变，常在常规影像学评估或患者因原发性疾病就诊时偶然发现。SANT具有复杂的病理表现、未知的自然发展过程且较为罕见，这使得临床医生和病理学家难以明确其真实性质。我们报告一例55岁男性患者，因体检偶然发现脾脏肿块前来就诊。他患有高血压和高脂血症，无明显临床症状。此后，他接受了脾脏手术切除，术后患者无特殊不适。我们的结果表明，手术切除对于无明显临床症状的SANT患者是一种有效的治疗方法，但也应考虑患者的综合情况。
