aThe Institute for Aging Research, Hebrew SeniorLife, Boston Massachusetts bDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts cDepartment of Allied Health Sciences, The University of Connecticut, Storrs, Connecticut, USA.
Curr Opin Clin Nutr Metab Care. 2014 Jan;17(1):69-74. doi: 10.1097/MCO.0000000000000013.
To underscore recent clinical studies, which evaluate the association between dietary protein and bone health.
Epidemiologic studies show greater protein intake to be beneficial to bone health in adults. In addition, randomized controlled trials show that protein's positive effect on bone health is augmented by increased calcium intake. The relation between dietary protein and fracture risk is unclear. Dietary protein may positively impact bone health by increasing muscle mass, increasing calcium absorption, suppressing parathyroid hormone, and augmenting insulin-like growth factor 1 production; but the effects of other factors that contribute to this association, such as dietary protein dose and timing response, require further research.
The positive effects of protein intake on bone health may only be beneficial under conditions of adequate calcium intake. Dietary protein's relation with fracture risk requires further investigation.
强调最近的临床研究，评估饮食蛋白与骨骼健康之间的关系。
流行病学研究表明，成年人摄入更多的蛋白质对骨骼健康有益。此外，随机对照试验表明，增加钙的摄入可以增强蛋白质对骨骼健康的积极影响。饮食蛋白与骨折风险之间的关系尚不清楚。饮食蛋白可能通过增加肌肉质量、增加钙吸收、抑制甲状旁腺激素和增加胰岛素样生长因子 1 的产生来积极影响骨骼健康；但是，其他有助于这种关联的因素的影响，如饮食蛋白剂量和时间反应，需要进一步研究。
蛋白质摄入对骨骼健康的积极影响可能只有在摄入足够钙的情况下才有益。饮食蛋白与骨折风险的关系需要进一步研究。
