Tan Kelvin H, Sabapathy Antoinette, Wei Xing
Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, Singapore, 229899.
Cochrane Database Syst Rev. 2013 Dec 7;2013(12):CD003396. doi: 10.1002/14651858.CD003396.pub2.
Manual fetal manipulation has been suggested to improve the efficiency of antepartum fetal heart rate testing.
The objective of this review was to assess the merits or adverse effects of the use of manual fetal manipulation in conjunction with tests of fetal wellbeing.
We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 September 2013).
All published and unpublished randomised controlled trials assessing the use of fetal manipulation versus mock stimulation, no stimulation or other types of stimulation, used in conjunction with cardiotocography or other tests of fetal wellbeing.
Three review authors independently assessed studies for inclusion, assessed trial quality and extracted data. Data were checked for accuracy. We contacted authors of published and unpublished trials for further information.
We included four trials with a total of 1280 women with 2670 episodes of participation. No trial was at low risk of bias for all domains and only two trials were at low risk of bias for both selection and attrition bias.Fetal manual manipulation decreased the incidence of non-reactive antenatal cardiotocography test compared to mock or no stimulation. However, this was not statistically significant (average risk ratio (RR) 0.31, 95% confidence interval (CI) 0.02 to 6.20, I² = 96%; two trials, N = 2350). There was also no significant reduction in the mean testing time to achieve a reactive result (mean difference -2.29 minutes, 95% CI -9.61 minutes to 5.03 minutes, I² = 97%; two trials, N = 560).Comparing fetal manual manipulation with vibroacoustic stimulation, there was no significant difference in the incidence of non-reactive cardiotocography or the need for contraction-stress test.There were no data available on other outcomes such as perinatal mortality, fetal distress, maternal anxiety and gestation at delivery.
AUTHORS' CONCLUSIONS: There is insufficient evidence to support the use of manual fetal manipulation during cardiotocography or other tests of fetal wellbeing. More studies of manual fetal manipulation that utilises standardised protocol should be encouraged.
有人提出手动胎儿操作可提高产前胎儿心率检测的效率。
本综述的目的是评估在胎儿健康检测中使用手动胎儿操作的优点或不良影响。
我们检索了Cochrane妊娠与分娩组试验注册库(2013年9月30日)。
所有已发表和未发表的随机对照试验,评估与宫缩图或其他胎儿健康检测联合使用的胎儿操作与模拟刺激、无刺激或其他类型刺激的效果。
三位综述作者独立评估纳入研究、评估试验质量并提取数据。检查数据准确性。我们联系了已发表和未发表试验的作者以获取更多信息。
我们纳入了四项试验,共1280名女性参与2670次试验。没有一项试验在所有领域均处于低偏倚风险,只有两项试验在选择和失访偏倚方面处于低偏倚风险。与模拟或无刺激相比,手动胎儿操作降低了产前宫缩图检测无反应的发生率。然而,这在统计学上并不显著(平均风险比(RR)0.31,95%置信区间(CI)0.02至6.20,I² = 96%;两项试验,N = 2350)。在获得反应性结果的平均检测时间上也没有显著缩短(平均差 -2.29分钟,95% CI -9.61分钟至5.03分钟,I² = 97%;两项试验,N = 560)。将手动胎儿操作与声振刺激进行比较,在宫缩图检测无反应的发生率或缩宫素激惹试验的需求方面没有显著差异。没有关于其他结局的数据,如围产期死亡率、胎儿窘迫、母亲焦虑和分娩孕周。
没有足够的证据支持在宫缩图或其他胎儿健康检测中使用手动胎儿操作。应鼓励开展更多采用标准化方案的手动胎儿操作研究。