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美国男性和女性的种族、生命历程社会经济地位与糖尿病患病率之间的关联:一项基于人群的队列研究结果

Associations between race, lifecourse socioeconomic position and prevalence of diabetes among US women and men: results from a population-based panel study.

作者信息

Insaf T Z, Strogatz D S, Yucel R M, Chasan-Taber L, Shaw B A

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, State University of New York, Rensselaer, New York, USA.

出版信息

J Epidemiol Community Health. 2014 Apr;68(4):318-25. doi: 10.1136/jech-2013-202585. Epub 2013 Dec 6.

Abstract

BACKGROUND

Few studies have examined the degree to which racial disparities in the development of diabetes are accounted by differences in lifecourse socioeconomic position (SEP). We assessed the association between race, lifecourse SEP measures and prevalence of diabetes in a representative US sample of black and white adults.

METHODS

A generalised estimating equations approach was used with a sample of 3497 adults from the Americans' Changing Lives study. Sex-specific models were calculated to compute prevalence ratios (PR) for associations of race and SEP with self-reported diagnoses of diabetes.

RESULTS

For men, childhood and adult SEP were unrelated to diabetes, and adjustment for lifecourse SEP had little effect on the excess diabetes in blacks (PR=1.56, 95% CI 1.11 to 2.21). Adjustment for measures of lifecourse SEP reduced the PR for the association between race and diabetes in women from 1.96 (95% CI 1.52 to 2.54) to 1.40 (95% CI 1.04 to 1.87) with the respondent's education responsible for most of the reduction in the association. However, diabetes was also inversely associated with father's education, and low SEP throughout the lifecourse was associated with a nearly threefold increase in diabetes (PR=2.89, 95% CI 2.10 to 3.99).

CONCLUSIONS

Racial disparities in diabetes existed among both men and women, but lifecourse SEP was related to diabetes only among women. The pathway and cumulative hypotheses for lifecourse SEP effects on diabetes may be especially salient for women.

摘要

背景

很少有研究探讨糖尿病发展过程中的种族差异在多大程度上是由生命历程中的社会经济地位(SEP)差异所导致的。我们在美国黑人和白人成年人的代表性样本中评估了种族、生命历程SEP指标与糖尿病患病率之间的关联。

方法

采用广义估计方程方法,样本来自“美国人生活变化”研究中的3497名成年人。计算了按性别分类的模型,以计算种族和SEP与自我报告的糖尿病诊断之间关联的患病率比(PR)。

结果

对于男性,儿童期和成年期的SEP与糖尿病无关,对生命历程SEP进行调整对黑人中过多的糖尿病病例影响不大(PR = 1.56,95%可信区间1.11至2.21)。对生命历程SEP指标进行调整后,女性中种族与糖尿病之间关联的PR从1.96(95%可信区间1.52至2.54)降至1.40(95%可信区间1.(此处原文有误,应为1.04)至1.87),其中受访者的教育程度对关联的降低起了大部分作用。然而,糖尿病也与父亲的教育程度呈负相关,生命历程中低SEP与糖尿病患病率几乎增加两倍相关(PR = 2.89,95%可信区间2.10至3.99)。

结论

糖尿病的种族差异在男性和女性中均存在,但生命历程SEP仅与女性的糖尿病有关。生命历程SEP对糖尿病影响的途径和累积假说可能对女性尤为突出。

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