Adelman Burt
1Dyax Corporation, Burlington, MA; and.
Hematology Am Soc Hematol Educ Program. 2013;2013:311-5. doi: 10.1182/asheducation-2013.1.311.
Effective drug therapies are a cornerstone of medical practice. The path from drug discovery to approval is expensive and commonly associated with failure. The cost of drug development exceeds 800 million dollars per product. Late failure due to lack of clinical efficacy is a common cause of high costs. Recent attempts to improve the process of drug development involve the formation of public-private partnerships, which are facilitating the creation of new collaborations among corporate and nonprofit entities to find solutions that will accelerate innovative drug discovery.
有效的药物疗法是医学实践的基石。从药物发现到获批的过程成本高昂,且通常伴随着失败。每种药物的研发成本超过8亿美元。因缺乏临床疗效导致的后期失败是成本高昂的常见原因。最近为改进药物研发过程所做的尝试包括建立公私合作伙伴关系,这有助于在企业和非营利实体之间建立新的合作关系,以找到能够加速创新药物发现的解决方案。