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早期霍奇金淋巴瘤的治疗:放射治疗是否仍有作用?

Management of early-stage Hodgkin lymphoma: is there still a role for radiation?

作者信息

Johnson Peter W M

机构信息

1Cancer Research UK Centre, University of Southampton, Southampton, United Kingdom.

出版信息

Hematology Am Soc Hematol Educ Program. 2013;2013:400-5. doi: 10.1182/asheducation-2013.1.400.

DOI:10.1182/asheducation-2013.1.400
PMID:24319211
Abstract

Although radiotherapy is highly effective for the treatment of Hodgkin lymphoma, the realization of its potential long-term toxicity and the demonstration of excellent results from combination chemotherapy have led to a retreat from its use in early-stage disease. Recent trials using functional imaging may allow better identification of those patients for whom radiotherapy may be safely omitted without compromising cure rates and this review examines the evidence for this.

摘要

尽管放射疗法对霍奇金淋巴瘤的治疗非常有效,但认识到其潜在的长期毒性以及联合化疗显示出的优异效果,使得放射疗法在早期疾病治疗中的应用有所减少。最近使用功能成像的试验可能有助于更好地识别那些可以安全省略放射疗法而不影响治愈率的患者,本综述将审视这方面的证据。

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引用本文的文献

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Initial staging of Hodgkin's disease: role of contrast-enhanced 18F FDG PET/CT.
霍奇金淋巴瘤的初始分期:对比增强18F FDG PET/CT的作用
Medicine (Baltimore). 2014 Aug;93(8):e50. doi: 10.1097/MD.0000000000000050.