Institute for Medical Science and Technology (IMSaT), Wilson House, University of Dundee, Dundee DD2 1FD, UK.
Biomed Res Int. 2013;2013:526512. doi: 10.1155/2013/526512. Epub 2013 Nov 12.
Magnetic retraction offers advantages over physical retraction by graspers because of reduced tissue trauma. The objectives of this study are to investigate a novel method of magnetisation of bowel segments by intraluminal injection of magnetic glue and to demonstrate the feasibility of magnetic retraction of bowel with sufficient force during minimal access surgery. Following an initial materials characterisation study, selected microparticles of stainless steel (SS410- μ Ps) were mixed with chosen cyanoacrylate glue (Loctite 4014). During intraluminal injection of the magnetic glue using ex vivo porcine colonic segments, a magnetic probe placed at the injected site ensured that the SS410-μPs aggregated during glue polymerisation to form an intraluminal mucosally adherent coagulum. The magnetised colonic segments were retracted by magnetic probes (5 and 10 mm) placed external to the bowel wall. A tensiometer was used to record the retraction force. With an injected volume of 2 mL in a particle concentration of 1 g/mL, this technique produced maximal magnetic retraction forces of 2.24 ± 0.23 N and 5.11 ± 0.34 N (n = 20), with use of 5 and 10 mm probes, respectively. The results indicate that the formation of an intraluminal coagulum based on SS410- μPs and Loctite 4014 produces sufficient magnetic retraction for bowel retraction.
磁牵引相对于抓握器的物理牵引具有减少组织创伤的优势。本研究的目的是探讨一种通过腔内注射磁性胶来磁化肠段的新方法，并证明在微创外科中使用足够的力进行肠磁牵引的可行性。在进行初始材料特性研究后，选择不锈钢（SS410-μPs）的微颗粒与选定的氰基丙烯酸酯胶（乐泰 4014）混合。在使用离体猪结肠段进行腔内磁性胶注射时，将磁性探头放置在注射部位，以确保 SS410-μPs 在胶聚合过程中聚集，形成腔内黏膜附着的凝块。将磁性探头（5 毫米和 10 毫米）放置在肠壁外部来牵引磁化的结肠段。张力计用于记录牵引力。在 2 毫升的注射体积和 1 克/毫升的颗粒浓度下，该技术分别产生了 2.24±0.23 N 和 5.11±0.34 N（n=20）的最大磁牵引力，分别使用 5 毫米和 10 毫米探头。结果表明，基于 SS410-μPs 和乐泰 4014 的腔内凝块形成可产生足够的肠磁牵引以进行肠牵引。
