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褪黑素在绝经后女性睡眠障碍中的致病作用。

Pathogenic role of melatonin in sleep disorders in menopausal women.

作者信息

Kolesnikova L I, Madaeva I M, Semenova N V, Suturina L V, Berdina O N, Sholohov L F, Solodova E I

机构信息

Research Center of Family Health Protection and Human Reproduction Problems, Siberian Division of Russian Academy of Medical Sciences, Irkutsk, Russia.

出版信息

Bull Exp Biol Med. 2013 Nov;156(1):104-6. doi: 10.1007/s10517-013-2289-8.

DOI:10.1007/s10517-013-2289-8
PMID:24319702
Abstract

The data on circadian rhythms of melatonin secretion in women of perimenopausal (n=39) and postmenopausal (n=52) age are presented. Each group was divided into control (without sleep disorders) and main group (with sleep disorders). The saliva was collected 4 times a day (6.00-7.00, 12.00-13.00, 18.00-19.00, 23.00-24.00). The study revealed an association between sleep disorders and decreased level of melatonin only in women of perimenopausal age.

摘要

本文呈现了围绝经期(n = 39)和绝经后(n = 52)女性褪黑素分泌昼夜节律的数据。每组又分为对照组(无睡眠障碍)和主要组(有睡眠障碍)。每天采集4次唾液(6:00 - 7:00、12:00 - 13:00、18:00 - 19:00、23:00 - 24:00)。研究发现,仅在围绝经期女性中,睡眠障碍与褪黑素水平降低之间存在关联。

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