褪黑素在绝经后女性睡眠障碍中的致病作用。
Pathogenic role of melatonin in sleep disorders in menopausal women.
作者信息
Kolesnikova L I, Madaeva I M, Semenova N V, Suturina L V, Berdina O N, Sholohov L F, Solodova E I
机构信息
Research Center of Family Health Protection and Human Reproduction Problems, Siberian Division of Russian Academy of Medical Sciences, Irkutsk, Russia.
出版信息
Bull Exp Biol Med. 2013 Nov;156(1):104-6. doi: 10.1007/s10517-013-2289-8.
The data on circadian rhythms of melatonin secretion in women of perimenopausal (n=39) and postmenopausal (n=52) age are presented. Each group was divided into control (without sleep disorders) and main group (with sleep disorders). The saliva was collected 4 times a day (6.00-7.00, 12.00-13.00, 18.00-19.00, 23.00-24.00). The study revealed an association between sleep disorders and decreased level of melatonin only in women of perimenopausal age.
本文呈现了围绝经期（n = 39）和绝经后（n = 52）女性褪黑素分泌昼夜节律的数据。每组又分为对照组（无睡眠障碍）和主要组（有睡眠障碍）。每天采集4次唾液（6:00 - 7:00、12:00 - 13:00、18:00 - 19:00、23:00 - 24:00）。研究发现，仅在围绝经期女性中，睡眠障碍与褪黑素水平降低之间存在关联。
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