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镭疗法对妇科恶性肿瘤患者自然杀伤(NK)活性的早期影响。

Early effects of radium therapy on natural killer (NK) activity in patients with gynaecological malignancies.

作者信息

Frydecka I, Blok K, Kornafel J, Kuliczkowaski K, Polakowska A

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1986;113(4):499-505.

PMID:2431971
Abstract

The effect of radium therapy on NK activity in patients with gynecological cancer is presented. Patients were tested before treatment, immediately after treatment and at 1 week intervals for 2 weeks. NK activity in patients before treatment was not statistically different from the normal controls. There was a statistically significant decrease of NK activity after treatment compared to pretreatment value (p less than 0.001). After 1 week NK activity reached pretreatment value and did not change a week later. Radium therapy does not result in a long lasting depression of NK activity, the important host defense mechanism.

摘要

本文介绍了镭疗法对妇科癌症患者自然杀伤细胞(NK)活性的影响。在治疗前、治疗后即刻以及治疗后2周内每隔1周对患者进行检测。治疗前患者的NK活性与正常对照组相比无统计学差异。与治疗前相比,治疗后NK活性有统计学意义的下降(p<0.001)。1周后NK活性恢复到治疗前水平,且在之后1周未发生变化。镭疗法不会导致作为重要宿主防御机制的NK活性长期降低。

相似文献

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Early effects of radium therapy on natural killer (NK) activity in patients with gynaecological malignancies.镭疗法对妇科恶性肿瘤患者自然杀伤(NK)活性的早期影响。
Folia Haematol Int Mag Klin Morphol Blutforsch. 1986;113(4):499-505.
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Effect of bitter melon (Momordica charantia Linn) on level and function of natural killer cells in cervical cancer patients with radiotherapy.苦瓜(苦瓜属 Linn)对宫颈癌放疗患者自然杀伤细胞水平及功能的影响。
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Increased natural killer cell activity in uterine cervix cancer patients undergoing radiation therapy.接受放射治疗的子宫颈癌患者自然杀伤细胞活性增加。
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Influence of neoadjuvant polychemotherapy on natural killer cell activity in patients with locally advanced cervical squamous carcinoma.新辅助多药化疗对局部晚期宫颈鳞状癌患者自然杀伤细胞活性的影响。
Gynecol Oncol. 1994 Jan;52(1):39-43. doi: 10.1006/gyno.1994.1008.
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[The effect of sera of breast cancer patients on NK cell activity].[乳腺癌患者血清对自然杀伤细胞活性的影响]
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Natural killer and activated killer activities in chronic liver disease and hepatocellular carcinoma: evidence for a decreased lymphokine-induced activity of effector cells.慢性肝病和肝细胞癌中的自然杀伤细胞活性及活化杀伤细胞活性:效应细胞的淋巴因子诱导活性降低的证据。
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Early inhibition of natural and interferon-activated killers in endometrial cancer patients treated with local radiotherapy.接受局部放疗的子宫内膜癌患者中自然杀伤细胞和干扰素激活杀伤细胞的早期抑制作用
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[Complications in supervoltage therapy of uterine malignancies].
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NK cell activity in the presence of IL-12 is a prognostic assay to neoadjuvant chemotherapy in cervical cancer.白细胞介素-12存在下的自然杀伤细胞活性是宫颈癌新辅助化疗的一项预后检测指标。
Gynecol Oncol. 2000 Sep;78(3 Pt 1):318-23. doi: 10.1006/gyno.2000.5878.

引用本文的文献

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Long-term influence of adjuvant therapy on natural killer cell activity in breast cancer.辅助治疗对乳腺癌自然杀伤细胞活性的长期影响。
Cancer Immunol Immunother. 1988;27(3):278-82. doi: 10.1007/BF00205452.