Doerfer J, Wässer S, Breidenbach H, Domula M
Folia Haematol Int Mag Klin Morphol Blutforsch. 1986;113(4):506-14.
Hematological and coagulative-analytical findings are represented in 10 patients aged between 3 months and 12.9 years affected with a typical Kawasawski syndrome, a disease which, etiologically, has not been elucidated and which will predominantly occur at the early childhood. During the hemostaseological examinations the significantly increased fibrinogen level at the initial stage was particularly striking in 6 patients. Partially a considerable number of leukocytoses with a shift to the left appeared almost constantly during the acute stage of the disease. At the subacute stage, however, mostly moderate thrombocytoses could be detected. The differential-diagnostic as well as the therapeutic significance of such alterations and the present possibilities of treating them with acetylsalicylic acid or prednisolone respectively are evaluated.
对10例年龄在3个月至12.9岁之间患典型川崎病的患者进行了血液学和凝血分析检查。川崎病病因尚未阐明,主要发生在幼儿期。在止血检查中,6例患者在疾病初期纤维蛋白原水平显著升高尤为明显。在疾病急性期,部分患者几乎持续出现大量白细胞增多并伴有核左移。然而,在亚急性期,大多可检测到中度血小板减少。评估了这些改变的鉴别诊断及治疗意义,以及分别用阿司匹林或泼尼松龙治疗的可能性。