一锅法区域特异性合成咪唑并[1,2-a]吡啶：一种新型的、无金属的三组分反应，用于形成 C-N、C-O 和 C-S 键。
One-pot regiospecific synthesis of imidazo[1,2-a]pyridines: a novel, metal-free, three-component reaction for the formation of C-N, C-O, and C-S bonds.
机构信息
School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Guangzhou 510006, P.R. of China.
出版信息
Org Lett. 2014 Jan 3;16(1):146-9. doi: 10.1021/ol4031414. Epub 2013 Dec 9.
PMID:24320098
Abstract
A novel transition-metal-free three-component reaction for the construction of imidazo[1,2-a]pyridines has been developed. It represents a facile approach for the formation of C-N, C-O, and C-S bonds from ynals, pyridin-2-amines, and alcohols or thiols.
摘要
发展了一种新型的过渡金属自由三组分反应，用于构建咪唑并[1,2-a]吡啶。它代表了一种从炔醛、吡啶-2-胺、醇或硫醇形成 C-N、C-O 和 C-S 键的简便方法。
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