School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
J Org Chem. 2014 Jan 3;79(1):275-84. doi: 10.1021/jo4024304. Epub 2013 Dec 12.
A palladium-catalyzed oxidative coupling of arene C-H bonds with benzylic ethers via C-H bond activation is described. The reaction proceeds efficiently with a broad range of substrates bearing conventional directing groups with excellent functional group compatibility. This protocol potentially provides opportunities to use dibenzyl ethers as new acyl equivalents for catalytic acylation reactions.
本文描述了钯催化的芳基 C-H 键与苄醚的氧化偶联反应，通过 C-H 键的活化来实现。该反应具有广泛的底物适用性，可兼容传统导向基团，具有优异的官能团兼容性。该方法为使用二苄基醚作为新型酰基等价物进行催化酰化反应提供了可能。
