Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Aust Dent J. 2013 Dec;58(4):478-82. doi: 10.1111/adj.12110.
The aim of this study was to investigate the effect of arginine and fluoride on the reduction of erosive wear.
Bovine enamel blocks were randomly allocated into four groups (n = 20) and exposed to: ESPR group (8% arginine, 1450 ppm sodium monofluorophosphate, calcium carbonate and titanium dioxide); ESen group (1450 ppm sodium monofluorophosphate, 5% potassium citrate); positive control PC group (1500 ppm sodium monofluorophosphate) and negative control NC group (water). The samples were submitted to six alternating cycles of demineralization-remineralization (cola, 10 minutes; artificial saliva, 1 hour, respectively). Before and between cyclic demineralization and remineralization, blocks were treated with slurries of the respective toothpastes or water (1 minute). Erosive tissue loss was analysed by microhardness and profilometry. Data were analysed by ANOVA and Tukey tests for individual comparisons among the groups (p < 0.05).
In microhardness, the ESPR (217.46 ± 55.45) group was significantly better than the other treatment groups (PC = 302.76 ± 96.10; ESen = 315.56 ± 74.56; p < 0.001). The ESPR group showed a similar loss to NC group (NC = 210.8 ± 49.98; p = 0.991). The mean erosion depth (+/- SE, μm) was detected between NC (14.37 ± 1.72) and dentifrices tested (ESPR (4.11 ± 1.34), ESen group (7.64 ± 1.61) and PC (8.20 ± 2.19) (p = 0.000).
From the results of the present study, the effectiveness of Sensitive Pro Relief in the prevention of erosive surface loss seems to be attributed to the possible effect of the arginine associated with fluoride.
本研究旨在探讨精氨酸和氟化物对减少侵蚀性磨损的影响。
将牛牙釉质块随机分为四组（n=20），并进行如下处理：ESP 组（8%精氨酸、1450ppm 单氟磷酸钠、碳酸钙和二氧化钛）；ESen 组（1450ppm 单氟磷酸钠、5%柠檬酸钾）；阳性对照组 PC 组（1500ppm 单氟磷酸钠）和阴性对照组 NC 组（水）。样品经过 6 个去矿化-再矿化交替循环（可乐，10 分钟；人工唾液，1 小时）。在每个脱矿和再矿化循环前后，用相应牙膏的糊剂或水（1 分钟）处理牙釉质块。通过显微硬度和轮廓测量分析侵蚀性组织损失。采用方差分析和 Tukey 检验进行组间个体比较（p<0.05）。
在显微硬度方面，ESP 组（217.46±55.45）显著优于其他处理组（PC 组=302.76±96.10；ESen 组=315.56±74.56；p<0.001）。ESP 组与 NC 组的损失相似（NC 组=210.8±49.98；p=0.991）。NC 组（14.37±1.72μm）和测试牙釉质块（ESP 组（4.11±1.34μm）、ESen 组（7.64±1.61μm）和 PC 组（8.20±2.19μm）之间的平均侵蚀深度（±SE，μm）差异显著（p=0.000）。
从本研究结果来看，Sensitive Pro Relief 牙膏在预防侵蚀性表面损失方面的有效性似乎归因于精氨酸与氟化物的联合作用。
