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估计全球创伤性脊髓损伤的发病率。

Estimating the global incidence of traumatic spinal cord injury.

机构信息

Monash Injury Research Institute, Monash University, Melbourne, Victoria, Australia.

School of Medicine at Flinders University, Prevention, Promotion and Primary Health Care Cluster, Adelaide, South Australia, Australia.

出版信息

Spinal Cord. 2014 Feb;52(2):117-22. doi: 10.1038/sc.2013.135. Epub 2013 Dec 10.

Abstract

STUDY DESIGN

Population modelling--forecasting.

OBJECTIVES

To estimate the global incidence of traumatic spinal cord injury (TSCI).

SETTING

An initiative of the International Spinal Cord Society (ISCoS) Prevention Committee.

METHODS

Regression techniques were used to derive regional and global estimates of TSCI incidence. Using the findings of 31 published studies, a regression model was fitted using a known number of TSCI cases as the dependent variable and the population at risk as the single independent variable. In the process of deriving TSCI incidence, an alternative TSCI model was specified in an attempt to arrive at an optimal way of estimating the global incidence of TSCI.

RESULTS

The global incidence of TSCI was estimated to be 23 cases per 1,000,000 persons in 2007 (179,312 cases per annum). World Health Organization's regional results are provided.

DISCUSSION

Understanding the incidence of TSCI is important for health service planning and for the determination of injury prevention priorities. In the absence of high-quality epidemiological studies of TSCI in each country, the estimation of TSCI obtained through population modelling can be used to overcome known deficits in global spinal cord injury (SCI) data. The incidence of TSCI is context specific, and an alternative regression model demonstrated how TSCI incidence estimates could be improved with additional data. The results highlight the need for data standardisation and comprehensive reporting of national level TSCI data. A step-wise approach from the collation of conventional epidemiological data through to population modelling is suggested.

摘要

研究设计

人群模型——预测。

目标

估计全球创伤性脊髓损伤(TSCI)的发病率。

背景

国际脊髓学会(ISCoS)预防委员会的一项倡议。

方法

回归技术用于推断 TSCI 发病率的区域和全球估计值。利用 31 项已发表研究的结果,使用已知数量的 TSCI 病例作为因变量,风险人群作为唯一的自变量,拟合回归模型。在推导 TSCI 发病率的过程中,指定了替代的 TSCI 模型,试图找到一种估计全球 TSCI 发病率的最佳方法。

结果

2007 年全球 TSCI 的发病率估计为每 100 万人 23 例(每年 179312 例)。提供了世界卫生组织的区域结果。

讨论

了解 TSCI 的发病率对于卫生服务规划和确定伤害预防重点非常重要。在每个国家都没有高质量的 TSCI 流行病学研究的情况下,可以通过人群模型来估计 TSCI,以弥补全球脊髓损伤(SCI)数据的已知缺陷。TSCI 的发病率是特定于背景的,替代回归模型展示了如何通过更多的数据来改进 TSCI 发病率估计。结果强调了数据标准化和全面报告国家一级 TSCI 数据的必要性。建议采用逐步的方法,从常规流行病学数据的收集到人群模型。

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