Doğan Mehmet, Akyel Ahmet, Bilgin Murat, Erat Mehmet, Çimen Tolga, Sunman Hamza, Efe Tolga Han, Açıkel Sadık, Yeter Ekrem
Department of Cardiology, Ministry of Health Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey
Department of Cardiology, Ministry of Health Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey.
Clin Appl Thromb Hemost. 2015 Mar;21(2):172-6. doi: 10.1177/1076029613515071. Epub 2013 Dec 9.
In this study, we aimed to investigate the relationship between neutrophil to lymphocyte ratio (NLR) and infarct-related artery (IRA) patency in patients with ST-segment elevation myocardial infarction (STEMI).
A total of 349 patients with STEMI were recruited to this retrospective study. Baseline characteristics were reviewed. Patency of IRA was evaluated by thrombolysis in myocardial infarction flow grade.
Of all patients, 293 patients formed the occluded IRA group and 56 patients formed the patent IRA group. The NLR was significantly higher in occluded IRA group (4.4 ± 4.1 vs 1.9 ± 1.1, P < .001). Glucose levels were also higher in occluded IRA group (171.3 ± 78.0 vs 144.7 ± 49.7, P = .022). Regression analysis demonstrated admission NLR and plasma glucose levels as independent predictors of IRA patency.
In this study, we found that admission NLR and glucose levels were higher in patients with occluded IRA than in patients with STEMI. We also found that NLR and glucose levels were independent predictors of IRA patency. Because hemogram is a cheap, fast, and widely available test, it can be used in daily practice as a predictor of IRA patency.
在本研究中，我们旨在探讨ST段抬高型心肌梗死（STEMI）患者中性粒细胞与淋巴细胞比值（NLR）与梗死相关动脉（IRA）通畅情况之间的关系。
本回顾性研究共纳入349例STEMI患者。回顾了基线特征。通过心肌梗死溶栓血流分级评估IRA的通畅情况。
所有患者中，293例患者组成IRA闭塞组，56例患者组成IRA通畅组。IRA闭塞组的NLR显著更高（4.4±4.1对1.9±1.1，P<.001）。IRA闭塞组的血糖水平也更高（171.3±78.0对144.7±49.7，P=.022）。回归分析表明入院时的NLR和血糖水平是IRA通畅情况的独立预测因素。
在本研究中，我们发现IRA闭塞的STEMI患者入院时的NLR和血糖水平高于IRA通畅的患者。我们还发现NLR和血糖水平是IRA通畅情况的独立预测因素。由于血常规检查是一种廉价、快速且广泛可用的检测方法，它可在日常实践中用作IRA通畅情况的预测指标。
