Suppr超能文献

耳鸣患者高频畸变产物耳声发射(DPOAE)值与血液学参数的关系。

The relationship of high-frequency distortion product otoacoustic emission (DPOAE) values with hematological parameters in tinnitus patients.

机构信息

Department of Otorhinolaryngology, Medical School, Bolu Abant Izzet Baysal University, Bolu, Turkey.

Department of Audiology, Medical School, Bolu Abant Izzet Baysal University, Bolu, Turkey.

出版信息

Eur Arch Otorhinolaryngol. 2019 Nov;276(11):3013-3019. doi: 10.1007/s00405-019-05585-4. Epub 2019 Aug 1.

Abstract

PURPOSE

In this study, we aimed to investigate whether there is any positive or negative correlation between high-frequency distortion product otoacoustic emission (DPOAE) values and mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) in tinnitus patients.

METHODS

The study was performed with 52 volunteers (27 females, 25 males) aged between 35 and 50 years who presented with tinnitus to the otolaryngology outpatient clinic of a tertiary care center. Pure voice audiometric examination, DPOAE measurement, complete blood count values of the study participants were examined.

RESULTS

In both ears, a significant and negative correlation was observed between 4000 and 8000 Hz airway and 4000 Hz bone conduction pathways with NLR rates (p < 0.05). A statistically significant relationship was found between the bone conduction pathway PTA and discrimination values for both ears and NLR s (p < 0.05). A positive correlation was detected between NLRs and DPOAE measurements recorded at 4444 Hz, 5000 Hz, 8000 Hz, 8889 Hz, 10,000 Hz and 11,429 Hz frequencies in the right and 4444 Hz, 5000 Hz, 6154 Hz, 8000 Hz, 10,000 Hz and 11,429 Hz frequencies in the left ears, respectively (p < 0.05).

CONCLUSIONS

We concluded that there is a significant correlation between high-frequency pure tone audiometry measurements and high frequency DPOAE measurements and NLR. Further studies are needed to determine the utility of NLR as a marker for the recognition and follow-up of hearing loss in patients with tinnitus.

摘要

目的

本研究旨在探讨耳鸣患者高频失真产物耳声发射(DPOAE)值与平均血小板体积(MPV)和中性粒细胞/淋巴细胞比值(NLR)之间是否存在正相关或负相关。

方法

该研究纳入了 52 名(27 名女性,25 名男性)年龄在 35 至 50 岁之间的志愿者,他们因耳鸣到三级保健中心的耳鼻喉科门诊就诊。对研究参与者进行了纯音听阈检查、DPOAE 测量和全血细胞计数。

结果

在双耳中,4000 至 8000 Hz 气道和 4000 Hz 骨导通路上的 NLR 率与 DPOAE 值呈显著负相关(p<0.05)。双耳骨导通路 PTA 和分辨值与 NLRs 之间存在统计学显著关系(p<0.05)。NLRs 与右耳 4444 Hz、5000 Hz、8000 Hz、8889 Hz、10000 Hz 和 11429 Hz 及左耳 4444 Hz、5000 Hz、6154 Hz、8000 Hz、10000 Hz 和 11429 Hz 的 DPOAE 测量值呈正相关(p<0.05)。

结论

我们得出结论,高频纯音测听测量值与高频 DPOAE 测量值和 NLR 之间存在显著相关性。需要进一步的研究来确定 NLR 作为识别和随访耳鸣患者听力损失的标志物的效用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验