卡马西平，一种抗惊厥药物，与对叔丁基杯[8]芳烃的分子识别研究。
Molecular recognition study of Carbamazepine, antiseizure drug, by p-t-butyl calix(8)arene.
机构信息
Department of Chemistry, Shri Meenakshi Government College for Women (Autonomous), Madurai 625 002, India.
Department of Laser Studies, School of Physics, Madurai Kamaraj University, Madurai 625 021, India.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Mar 25;122:447-50. doi: 10.1016/j.saa.2013.11.042. Epub 2013 Nov 20.
The formation of inclusion complex of Carbamazepine, a antiseizure drug molecule, with the supra molecule, p-t-butyl calix(8)arene was studied. p-t-Butyl calix(8)arene was the host molecule and Carbamazepine was the guest molecule. Optical absorption spectral studies were carried out to study the molecular recognition properties of p-t-butyl calix(8)arene with Carbamazepine. The stochiometry of the host-guest complex and the binding constant were determined.
对卡马西平（一种抗癫痫药物分子）与超分子 p-t-丁基杯[8]芳烃的包合配合物的形成进行了研究。p-t-丁基杯[8]芳烃是主体分子，卡马西平是客体分子。进行了光学吸收光谱研究，以研究 p-t-丁基杯[8]芳烃与卡马西平的分子识别特性。确定了主体-客体配合物的化学计量和结合常数。
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