Camiletti Alison L, Awde David N, Thompson Graham J
Biology Department, Western University, 1151 Richmond Street, London, ON, N6A 5B7, Canada,
Naturwissenschaften. 2014 Jan;101(1):25-31. doi: 10.1007/s00114-013-1125-3. Epub 2013 Dec 10.
In this study we test one central prediction from sociogenomic theory--that social and non-social taxa share common genetic toolkits that regulate reproduction in response to environmental cues. We exposed Drosophila females of rover (for(R)) and sitter (for(s)) genotypes to an ovary-suppressing pheromone derived from the honeybee Apis mellifera. Surprisingly, queen mandibular pheromone (QMP) affected several measures of fitness in flies, and in a manner comparable to the pheromone's normal effect on bee workers. QMP-treated sitter flies had smaller ovaries that contained fewer eggs than did untreated controls. QMP-treated rover flies, by contrast, showed a more variable pattern that only sometimes resulted in ovary inhibition, while a third strain of fly that contains a sitter mutant allele in a rover background (for(s2)) showed no ovarian response to QMP. Taken together, our results suggest that distinctly non-social insects have some capacity to respond to social cues, but that this response varies with fly genotype. In general, the interspecific response is consistent with a conserved gene set affecting reproductive physiology. The differential response among strains in particular suggests that for is itself important for modulating the fly's pheromonal response.
在本研究中，我们检验了社会基因组学理论的一个核心预测——即社会和非社会分类群共享共同的基因工具包，这些工具包可根据环境线索调节繁殖。我们将漫游型（for(R)）和留守型（for(s)）基因型的果蝇雌性暴露于源自蜜蜂（Apis mellifera）的抑制卵巢的信息素中。令人惊讶的是，蜂王下颚信息素（QMP）影响了果蝇的多项适合度指标，其方式与该信息素对蜜蜂工蜂的正常影响相当。经QMP处理的留守型果蝇的卵巢比未处理的对照果蝇更小，所含卵子也更少。相比之下，经QMP处理的漫游型果蝇表现出更具变异性的模式，只是有时会导致卵巢受到抑制，而在漫游型背景中含有一个留守型突变等位基因的第三种果蝇品系（for(s2)）对QMP没有卵巢反应。综合来看，我们的结果表明，截然不同的非社会性昆虫具有对社会线索做出反应的一定能力，但这种反应因果蝇基因型而异。一般来说，种间反应与影响生殖生理学的一组保守基因一致。特别是品系间的差异反应表明，for基因本身对于调节果蝇的信息素反应很重要。
