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Constitutive function of the Ikaros transcription factor in primary leukemia cells from pediatric newly diagnosed high-risk and relapsed B-precursor ALL patients.伊卡罗斯转录因子在儿科新诊断高危和复发 B 前体细胞 ALL 患者原始白血病细胞中的组成性功能。
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本文引用的文献

1
What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?Ikaros 基因缺失作为儿童费城阴性 B 细胞前体急性淋巴细胞白血病预后标志物的相关性如何？
Haematologica. 2013 Aug;98(8):1226-31. doi: 10.3324/haematol.2012.075432. Epub 2013 Apr 12.
2
Function of Ikaros as a tumor suppressor in B cell acute lymphoblastic leukemia.Ikaros作为B细胞急性淋巴细胞白血病肿瘤抑制因子的功能。
Am J Blood Res. 2013;3(1):1-13. Epub 2013 Jan 17.
3
Diagnostic value of DNA alteration: loss of heterozygosity or allelic imbalance-promising for molecular staging of prostate cancers.DNA 改变的诊断价值：杂合性丢失或等位基因失衡——有望用于前列腺癌的分子分期。
Med Oncol. 2013 Mar;30(1):391. doi: 10.1007/s12032-012-0391-9. Epub 2013 Jan 4.
4
Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros.丝氨酸磷酸化由 SYK 介导对于 Ikaros 的核定位和转录因子功能至关重要。
Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18072-7. doi: 10.1073/pnas.1209828109. Epub 2012 Oct 15.
5
Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.流式细胞术检测伊卡罗斯（IKZF1）改变和第 15 天微小残留病可预测儿童 BCR/ABL 阴性急性淋巴细胞白血病的预后。
Pediatr Blood Cancer. 2013 Mar;60(3):420-7. doi: 10.1002/pbc.24299. Epub 2012 Sep 19.
6
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.IKZF1 缺失是根据 ALL-BFM 2000 方案治疗的儿童急性淋巴细胞白血病患者结局的独立预测因子。
Haematologica. 2013 Mar;98(3):428-32. doi: 10.3324/haematol.2011.056135. Epub 2012 Aug 8.
7
Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study.CRLF2、IKZF1、JAK 与儿童急性淋巴细胞白血病微小残留病灶联合构建预后模型：儿童肿瘤协作组研究。
Blood. 2012 Apr 12;119(15):3512-22. doi: 10.1182/blood-2011-11-394221. Epub 2012 Feb 24.
8
Antigen receptor allelic exclusion: an update and reappraisal.抗原受体等位基因排斥：最新进展与重新评估
J Immunol. 2010 Oct 1;185(7):3801-8. doi: 10.4049/jimmunol.1001158.
9
Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group.基于微阵列的基因表达谱分析在白血病诊断和亚分类中的临床应用：来自国际白血病微阵列创新研究组的报告。
J Clin Oncol. 2010 May 20;28(15):2529-37. doi: 10.1200/JCO.2009.23.4732. Epub 2010 Apr 20.
10
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.IKZF1缺失与急性淋巴细胞白血病的预后
N Engl J Med. 2009 Jan 29;360(5):470-80. doi: 10.1056/NEJMoa0808253. Epub 2009 Jan 7.

Incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia.

作者信息

Qazi Sanjive, Uckun Fatih M

出版信息

Haematologica. 2013 Dec;98(12):e151-2. doi: 10.3324/haematol.2013.091140.

DOI:10.3324/haematol.2013.091140
PMID:24323986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3856976/
Abstract
摘要