小管腺瘤免疫表型：一例报告
Canalicular adenoma immunoprofile: a case report.
作者信息
Sivolella Stefano, Valente Marialuisa, De Biagi Marleen, Mazzoleni Sergio, Stellini Edoardo
机构信息
Institute of Clinical Dentistry, Department of Neurosciences, Neurological, Psychiatric, Sensorial, Reconstructive and Rehabilitative Sciences, University of Padova, Padova, Italy.
出版信息
Gerodontology. 2014 Dec;31(4):320-4. doi: 10.1111/ger.12039. Epub 2013 Dec 11.
OBJECTIVES
To report a case of canalicular adenoma (CA) and discuss the use of immunohistochemistry to better address the diagnosis given some unusual characteristics in this patient.
BACKGROUND
CA is an uncommon benign neoplasm that can develop in minor salivary gland duct tissues throughout the oral cavity. At histology, it shares several features with other salivary tumors. Immunohistochemistry can be useful in the differential diagnosis.
MATERIALS AND METHODS
The clinical presentation consisted in a nodule on the left upper lip of an 85-year-old man. The patient's main complaint was upper denture instability secondary to soft tissue changes. The nodule was excised under local anesthesia and underwent histological and immunohistochemical examination to rule out any malignancy.
RESULTS
Histological findings, cytokeratin positivity and the absence of any reactivity to specific markers of myoepithelial differentiation confirmed the epithelial nature of the lesion.
CONCLUSION
The histological diagnosis of benign salivary tumors such as CA can be confirmed by immunohistochemistry.
目的
报告一例小管腺瘤（CA）病例，并讨论鉴于该患者一些不寻常特征，免疫组织化学在更好地进行诊断方面的应用。
背景
CA是一种罕见的良性肿瘤，可发生于口腔内的小唾液腺导管组织。在组织学上，它与其他唾液腺肿瘤有一些共同特征。免疫组织化学在鉴别诊断中可能有用。
材料与方法
临床表现为一名85岁男性左上唇的一个结节。患者的主要诉求是由于软组织变化导致上假牙不稳定。该结节在局部麻醉下切除，并进行了组织学和免疫组织化学检查以排除任何恶性肿瘤。
结果
组织学发现、细胞角蛋白阳性以及对肌上皮分化的特定标志物无任何反应，证实了病变的上皮性质。
结论
免疫组织化学可证实CA等良性唾液腺肿瘤的组织学诊断。
Zotero 插件