• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

仅用降钙素原监测腹部脓毒症的治疗反应——要是真这么简单就好了!

Monitoring treatment response in abdominal sepsis with procalcitonin--if only!

作者信息

Eckmann Christian, Sanchez-Garcia Miguel

出版信息

Crit Care. 2013 Dec 10;17(6):1017. doi: 10.1186/cc13154.

DOI:10.1186/cc13154
PMID:24326175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4056891/
Abstract

The ideal management of infection includes not only the early identification and start of effective therapy but also the correct categorization of non-infected patients in order to avoid unnecessary use of antimicrobials. The availability of a specific and sensitive test for the presence of infection is of paramount importance to improve the prudent use of antimicrobial therapy. Procalcitonin (PCT) has been evaluated over recent years as to whether it can be used to detect the presence of different types of infection, allows reduced duration of antibiotic therapy, or predicts treatment failure or adverse outcome. In the previous issue of Critical Care, Jung and colleagues report about the monitoring of treatment response in abdominal sepsis by repetitive determination of PCT.

摘要

感染的理想管理不仅包括早期识别和开始有效的治疗,还包括对未感染患者进行正确分类,以避免不必要地使用抗菌药物。拥有一种针对感染存在的特异性和敏感性检测方法对于促进抗菌治疗的合理使用至关重要。近年来,人们对降钙素原(PCT)进行了评估,以确定它是否可用于检测不同类型感染的存在、缩短抗生素治疗时间,或预测治疗失败或不良结局。在上一期的《重症监护》杂志中,荣格及其同事报告了通过重复测定PCT来监测腹部脓毒症治疗反应的情况。

相似文献

1
Monitoring treatment response in abdominal sepsis with procalcitonin--if only!仅用降钙素原监测腹部脓毒症的治疗反应——要是真这么简单就好了!
Crit Care. 2013 Dec 10;17(6):1017. doi: 10.1186/cc13154.
2
Procalcitonin biomarker kinetics fails to predict treatment response in perioperative abdominal infection with septic shock.降钙素原生物标志物动力学无法预测围手术期腹部感染伴感染性休克的治疗反应。
Crit Care. 2013 Oct 24;17(5):R255. doi: 10.1186/cc13082.
3
[Role of procalcitonin in monitoring the antibiotic therapy in septic surgical patients].[降钙素原在监测脓毒症外科患者抗生素治疗中的作用]
Chirurgia (Bucur). 2012 Jan-Feb;107(1):71-8.
4
Biomarkers in the critically ill patient: procalcitonin.危重症患者的生物标志物:降钙素原。
Crit Care Clin. 2011 Apr;27(2):253-63. doi: 10.1016/j.ccc.2011.01.002.
5
Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial.使用降钙素原缩短脓毒症患者抗生素治疗疗程:一项随机试验。
Am J Respir Crit Care Med. 2008 Mar 1;177(5):498-505. doi: 10.1164/rccm.200708-1238OC. Epub 2007 Dec 20.
6
Procalcitonin-guided therapy in intensive care unit patients with severe sepsis and septic shock--a systematic review and meta-analysis.重症监护病房中严重脓毒症和脓毒性休克患者的降钙素原指导治疗——一项系统评价和荟萃分析。
Crit Care. 2013 Dec 11;17(6):R291. doi: 10.1186/cc13157.
7
Procalcitonin-guided therapy may reduce length of antibiotic treatment in intensive care unit patients with secondary peritonitis: A multicenter retrospective study.降钙素原引导治疗可能会缩短重症监护病房继发性腹膜炎患者的抗生素治疗时长:一项多中心回顾性研究。
J Crit Care. 2015 Jun;30(3):537-42. doi: 10.1016/j.jcrc.2014.12.014. Epub 2014 Dec 31.
8
Clinical and economic impact of procalcitonin to shorten antimicrobial therapy in septic patients with proven bacterial infection in an intensive care setting.降钙素原在重症监护病房确诊细菌性感染脓毒症患者中缩短抗菌治疗的临床和经济影响。
Diagn Microbiol Infect Dis. 2013 Jul;76(3):266-71. doi: 10.1016/j.diagmicrobio.2013.03.027. Epub 2013 May 25.
9
The usefulness of the semiquantitative procalcitonin test kit as a guideline for starting antibiotic administration.半定量降钙素原检测试剂盒作为启动抗生素治疗指南的实用性。
Am J Emerg Med. 2009 Sep;27(7):859-63. doi: 10.1016/j.ajem.2008.06.021.
10
The efficacy of procalcitonin as a biomarker in the management of sepsis: slaying dragons or tilting at windmills?降钙素原作为脓毒症管理中生物标志物的功效:屠龙之举还是徒劳无功?
Surg Infect (Larchmt). 2013 Dec;14(6):489-511. doi: 10.1089/sur.2012.028. Epub 2013 Nov 25.

引用本文的文献

1
The role of procalcitonin in the diagnosis of bacterial infection after major abdominal surgery: Advantage from daily measurement.降钙素原在腹部大手术后细菌感染诊断中的作用:每日检测的优势
Medicine (Baltimore). 2018 Jan;97(3):e9496. doi: 10.1097/MD.0000000000009496.
2
Intra-abdominal candidiasis: it's still a long way to get unquestionable data.腹腔念珠菌病:要获得确凿的数据仍有很长的路要走。
Intensive Care Med. 2015 Sep;41(9):1682-4. doi: 10.1007/s00134-015-3894-y. Epub 2015 Jun 19.

本文引用的文献

1
Procalcitonin biomarker kinetics fails to predict treatment response in perioperative abdominal infection with septic shock.降钙素原生物标志物动力学无法预测围手术期腹部感染伴感染性休克的治疗反应。
Crit Care. 2013 Oct 24;17(5):R255. doi: 10.1186/cc13082.
2
Procalcitonin decrease over 72 hours in US critical care units predicts fatal outcome in sepsis patients.在美国重症监护病房中,脓毒症患者降钙素原在72小时内下降预示着致命结局。
Crit Care. 2013 Jun 20;17(3):R115. doi: 10.1186/cc12787.
3
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.拯救脓毒症运动:严重脓毒症和脓毒性休克管理国际指南,2012 年。
Intensive Care Med. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Epub 2013 Jan 30.
4
Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial.降钙素原指导抗感染治疗以增加早期适当使用抗生素并改善重症监护病房患者的生存率:一项随机试验。
Crit Care Med. 2011 Sep;39(9):2048-58. doi: 10.1097/CCM.0b013e31821e8791.
5
Antimicrobial treatment of "complicated" intra-abdominal infections and the new IDSA guidelines ? a commentary and an alternative European approach according to clinical definitions.“复杂”腹腔内感染的抗菌治疗与新 IDSA 指南——根据临床定义的评论和另一种欧洲方法。
Eur J Med Res. 2011 Mar 28;16(3):115-26. doi: 10.1186/2047-783x-16-3-115.
6
Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.降钙素原在 ICU 减少患者抗生素暴露的应用(PRORATA 试验):一项多中心随机对照试验。
Lancet. 2010 Feb 6;375(9713):463-74. doi: 10.1016/S0140-6736(09)61879-1. Epub 2010 Jan 25.
7
Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.不恰当的抗菌治疗会导致人类感染性休克的生存率降低五倍。
Chest. 2009 Nov;136(5):1237-1248. doi: 10.1378/chest.09-0087. Epub 2009 Aug 20.
8
The cost of failure.
Surg Infect (Larchmt). 2008 Jun;9(3):313-5. doi: 10.1089/sur.2007.9964.
9
Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial.使用降钙素原缩短脓毒症患者抗生素治疗疗程:一项随机试验。
Am J Respir Crit Care Med. 2008 Mar 1;177(5):498-505. doi: 10.1164/rccm.200708-1238OC. Epub 2007 Dec 20.
10
Epidemiology of sepsis in Germany: results from a national prospective multicenter study.德国脓毒症流行病学:一项全国性前瞻性多中心研究的结果
Intensive Care Med. 2007 Apr;33(4):606-18. doi: 10.1007/s00134-006-0517-7. Epub 2007 Feb 24.