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成功施行Ⅰ型 Boston 角膜移植术后 Müller 肌-结膜切除术。

Successful Müller muscle-conjunctiva resection in patients with Boston keratoprosthesis type I.

机构信息

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL.

出版信息

Cornea. 2014 Mar;33(3):240-2. doi: 10.1097/ICO.0000000000000043.

DOI:10.1097/ICO.0000000000000043
PMID:24326330
Abstract

PURPOSE

To present a case series of patients with Boston keratoprosthesis type I (KPro) who have had successful ptosis repair with Müller muscle-conjunctiva resection (MMCR).

METHODS

Patients with KPros managed with MMCR for ptosis were identified. Records were examined to obtain preoperative and postoperative visual acuity, KPro viability, and eyelid measurements including margin-to-reflex distance 1 (MRD1), levator function, and lagophthalmos.

RESULTS

Seven eyes of 6 patients with KPros and ptosis treated with MMCR were identified. Four eyes underwent a lower lid tarsal strip procedure concurrently with the MMCR to minimize the risk of exposure to the graft postoperatively. The average time between KPro surgery and ptosis surgery was 29.1 months (range, 4-79 months). Preoperatively, the average MRD1 was -2.4 mm and the average levator function was 11.3 mm. Postoperatively, all eyelids were elevated and the average MRD1 was 0.9 mm. One eye had 0.5 mm of lagophthalmos noted whereas all other eyes had no lagophthalmos. The average follow-up time was 25.9 months (range, 13-41 months). All 7 eyes maintained a viable KPro without any compromise to the conjunctiva or donor corneal tissue.

CONCLUSIONS

This retrospective case series describes 7 eyes with KPros that underwent successful MMCR without compromise to the integrity of the KPro. Because these patients are at high risk for potential complications, we recommend careful patient selection, a goal of undercorrection, and consideration of supplemental procedures to the lower eyelids to minimize complications to the KPro.

摘要

目的

介绍一组波士顿Ⅰ型角膜表面镜(KPro)患者的病例系列,这些患者通过 Müller 肌-结膜切除术(MMCR)成功修复了上睑下垂。

方法

确定了接受 MMCR 治疗 KPro 上睑下垂的患者。检查病历以获得术前和术后视力、KPro 存活率以及包括睑缘至反射距离 1(MRD1)、提上睑肌功能和睑裂闭合在内的眼睑测量值。

结果

确定了 6 例 KPro 伴上睑下垂患者的 7 只眼接受了 MMCR 治疗。为了降低术后移植物暴露的风险,4 只眼同时行下睑睑板条切除术。KPro 手术和上睑下垂手术之间的平均时间为 29.1 个月(范围,4-79 个月)。术前,平均 MRD1 为-2.4mm,平均提上睑肌功能为 11.3mm。术后,所有眼睑均抬起,平均 MRD1 为 0.9mm。1 只眼有 0.5mm 的睑裂闭合不全,而所有其他眼均无睑裂闭合不全。平均随访时间为 25.9 个月(范围,13-41 个月)。所有 7 只眼均保持 KPro 存活,结膜和供体角膜组织均无损伤。

结论

本回顾性病例系列描述了 7 只 KPro 眼通过 MMCR 成功修复,而不影响 KPro 的完整性。由于这些患者存在潜在并发症的高风险,我们建议仔细选择患者,目标是轻度矫正,并考虑对下眼睑进行补充手术,以最大限度地减少对 KPro 的并发症。

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