Wang Jing, Byers Lauren Averett
1Departments of Bioinformatics and Computational Biology and 2Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Cancer Discov. 2013 Dec;3(12):1333-5. doi: 10.1158/2159-8290.CD-13-0790.
Jahchan and colleagues report the use of a biostatistical analysis to identify effective therapeutics for small cell lung cancer (SCLC). Their results reveal a new use for the tricyclic antidepressant imipramine in SCLC and shed light on the therapeutic potential of drug repositioning in cancer and other diseases.
贾昌及其同事报告了使用生物统计学分析来确定小细胞肺癌(SCLC)的有效治疗方法。他们的结果揭示了三环抗抑郁药丙咪嗪在小细胞肺癌中的新用途,并阐明了药物重新定位在癌症和其他疾病中的治疗潜力。