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伴刀豆球蛋白A刺激的小鼠抗可的松胸腺细胞产生淋巴因子。III. 抗Lyt抗体细胞毒性预处理对白细胞介素-2和干扰素产生细胞的影响。

Production of lymphokines by murine cortisone resistant thymocytes stimulated by concanavalin A. III. Effect of cytotoxic pretreatment with anti-Lyt antibodies on interleukin-2 and interferon producing cells.

作者信息

Pajtasz E, Kuśnierczyk P, Albin M, Kisielow P

出版信息

Arch Immunol Ther Exp (Warsz). 1986;34(4):403-7.

PMID:2432850
Abstract

Lyt phenotypes of interleukin-2 and interferon producing Balb/c cortisone resistant thymocytes, stimulated by concanavalin A in vitro, were studied using cytotoxic anti-Lyt-1.2 and anti-Lyt-2.2 alloantisera and monoclonal antibodies. It was found that while interleukin-2 was produced by both Lyt1+ and Lyt2+ cells, the ability to secrete IFN was limited to Lyt2+ cells only.

摘要

利用细胞毒性抗Lyt-1.2和抗Lyt-2.2同种抗血清及单克隆抗体,研究了体外经刀豆蛋白A刺激的白细胞介素-2和干扰素产生性Balb/c可的松抗性胸腺细胞的Lyt表型。结果发现,虽然Lyt1+和Lyt2+细胞均可产生白细胞介素-2,但分泌干扰素的能力仅限于Lyt2+细胞。

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