Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College of London, London, United Kingdom.
Epilepsia. 2013 Dec;54 Suppl 9:44-9. doi: 10.1111/epi.12443.
Functional imaging studies complement structural magnetic resonance imaging (MRI) in the assessment of patients with brain tumor-associated focal epilepsy. (11)C-Methionine (MET) and (18) F-fluoro-ethyl-L-tyrosine (FET) are amino acid analogues that highlight metabolically active areas in positron emission tomography (PET). Ictal single photon emission computed tomography (SPECT) can provide information about perilesional areas of seizure onset and early propagation. Functional MRI (fMRI) and diffusion tensor imaging (DTI) allow noninvasive identification of potentially eloquent motor, sensory, and language cortical areas and pathways with an accuracy of 10-15 mm compared to electrocortical stimulation (ECS). Repetitive navigated transcranial magnetic stimulation (TMS) allows even more precise noninvasive delineation of primary motor cortex. Information from functional imaging studies helps in the planning of brain tumor biopsies, resections, and the planning of intracranial video-electroencephalography (EEG) studies.
功能影像学研究在评估脑肿瘤相关局灶性癫痫患者方面补充了结构磁共振成像（MRI）。（11）C-蛋氨酸（MET）和（18）F-氟乙基-L-酪氨酸（FET）是正电子发射断层扫描（PET）中突出代谢活跃区域的氨基酸类似物。发作期单光子发射计算机断层扫描（SPECT）可以提供关于发作起始和早期传播的病变周围区域的信息。功能磁共振成像（fMRI）和弥散张量成像（DTI）允许无创性识别潜在的运动、感觉和语言皮质区域和通路，与电皮质刺激（ECS）相比，其准确性为 10-15 毫米。重复导航经颅磁刺激（TMS）甚至可以更精确地无创性描绘原发性运动皮质。功能影像学研究的信息有助于脑肿瘤活检、切除以及颅内视频脑电图（EEG）研究的规划。
