Sharma Vijay K, Yohanna Kusuma, Kawnayn Ghulam, Sarkar Nabin, Batra Amit
Division of Neurology, Department of Medicine, National University Hospital, Tower Block, Level 10, 1E Kent Ridge Road Singapore 119228.
Recent Pat CNS Drug Discov. 2013 Dec;8(3):205-19. doi: 10.2174/1574889808666131209124519.
Currently employed diagnostic ultrasonography provides clinically relevant information about cerebral hemodynamic changes in patients with cerebrovascular ischemia. The information thus obtained is often helpful to the physician for establishing or confirming the diagnosis and prognosis as well as in taking appropriate therapeutic decisions. It is associated with a high temporal resolution and can be performed bedside for rapid diagnosis as well as prolonged monitoring. Transcranial Doppler (TCD) ultrasonography is a non-invasive diagnostic modality that provides physiological information regarding various intracranial hemodynamic alterations in patients with cerebrovascular ischemia. Extended applications of TCD are useful in understanding various pathophysiological mechanisms responsible for the clinical manifestations of cerebrovascular ischemia. Thus, TCD is aptly called as the 'stethoscope' of a stroke neurologist. Cerebrovascular ultrasonography is considered as an essential component of a comprehensive stroke center. We have reviewed various recent patents pertaining to the applications of cerebrovascular ultrasonography employed in the selection of stroke patients for various therapeutic interventions.
目前使用的诊断性超声检查可提供有关脑血管缺血患者脑血流动力学变化的临床相关信息。由此获得的信息通常有助于医生进行诊断、确诊和判断预后，以及做出适当的治疗决策。它具有高时间分辨率，可在床边进行，以便快速诊断和长期监测。经颅多普勒（TCD）超声检查是一种非侵入性诊断方法，可提供有关脑血管缺血患者各种颅内血流动力学改变的生理信息。TCD的扩展应用有助于理解导致脑血管缺血临床表现的各种病理生理机制。因此，TCD被恰当地称为中风神经科医生的“听诊器”。脑血管超声检查被认为是综合卒中中心的重要组成部分。我们回顾了最近与脑血管超声检查在选择中风患者进行各种治疗干预中的应用相关的各种专利。
