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化脓性汗腺炎的两阶段手术:分阶段人工真皮和皮肤移植。

Two-stage surgery for hidradenitis suppurativa: staged artificial dermis and skin grafting.

机构信息

Department of Plastic and Reconstructive Surgery, University of Tokushima Graduate School, Tokushima, Japan.

出版信息

Dermatol Surg. 2014 Feb;40(2):110-5. doi: 10.1111/dsu.12400. Epub 2013 Dec 16.

Abstract

BACKGROUND

Hidradenitis suppurativa is a chronic and often refractory skin disease that can require radical excision of the full layer of fatty tissue under the lesion. Closure using a split-thickness skin graft often results in depression deformity and lack of tissue flexibility. We have developed a two-stage procedure to preserve fatty tissue during radical excision and apply an artificial dermis graft, and we have performed this procedure in 18 patients (33 lesions).

OBJECTIVE

To describe our two-stage procedure and report results of the procedure in our patient series.

METHODS

In the first step, all diseased skin including the superficial subcutaneous fatty tissue is excised; normal deep subcutaneous fatty tissue is preserved. Artificial dermis is then grafted to the preserved fatty tissue. Two weeks later, split-thickness skin grafts are applied to the skin defects. We evaluated graft success, any recurrence, and postoperative appearance in our patients, who were followed up for 8 to 36 months.

RESULTS

All 32 skin grafts were successful. There was only one recurrence, which was treated using reoperation, and postoperative appearances were good.

CONCLUSIONS

Our new procedure incorporating artificial dermis appears to be a good treatment option for advanced hidradenitis suppurativa.

摘要

背景

化脓性汗腺炎是一种慢性且常难治愈的皮肤疾病,可能需要彻底切除病变下的全层脂肪组织。使用断层皮片移植进行闭合通常会导致凹陷畸形和组织缺乏柔韧性。我们开发了一种两阶段手术方法,在彻底切除过程中保留脂肪组织并应用人工真皮移植物,我们已经对 18 名患者(33 处病变)进行了该手术。

目的

描述我们的两阶段手术并报告我们患者系列的手术结果。

方法

在第一阶段,切除所有病变皮肤,包括浅皮下脂肪组织;保留正常的深皮下脂肪组织。然后将人工真皮移植到保留的脂肪组织上。两周后,将断层皮片应用于皮肤缺损处。我们评估了患者的移植物成功率、任何复发情况以及术后外观,患者的随访时间为 8 至 36 个月。

结果

32 处皮肤移植物全部成功。仅发生 1 例复发,经再次手术治疗后得到治愈,术后外观良好。

结论

我们的新手术方法结合了人工真皮,似乎是治疗化脓性汗腺炎的一种良好选择。

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