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化脓性汗腺炎的外科治疗

Surgical Management of Hidradenitis Suppurativa.

作者信息

Krajewski Aleksandra, Alsayed Ahmed, Capek Allison, Casey Kathleen, Chandawarkar Rajiv

机构信息

From the Division of Plastic Surgery, Stonybrook University, Stonybrook, N.Y.

Department of Plastic Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio.

出版信息

Plast Reconstr Surg Glob Open. 2024 Jun 13;12(6):e5860. doi: 10.1097/GOX.0000000000005860. eCollection 2024 Jun.

DOI:10.1097/GOX.0000000000005860
PMID:38872991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11175856/
Abstract

Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory disease of the skin, characterized by recurrent draining sinuses and abscesses, predominantly in skin folds carrying terminal hairs and apocrine glands. Treatment for this debilitating disease has been medical management with antibiotics and immune modulators. With the advent of better reconstructive surgical techniques, the role of surgery in the treatment of HS has expanded, from being a last resort to a modality that is deployed earlier. Larger defects can be more easily reconstructed, allowing for a more radical excision of diseased areas. Locoregional flaps, perforator flaps, and propeller flaps that use the fasciocutaneous tissue allow reconstruction of defects with similar tissue, and provide better cosmetic and functional outcomes. They are easy to execute and can be performed even in resource-poor settings with concurrent use of immune modulators and postoperative antibiotics. Hidradenitis can be successfully treated with surgery in early stages as well as severe disease, due to the advances in understanding disease behavior, multidisciplinary care, and advanced reconstructive techniques. Coupled with a multidisciplinary care team, surgery offers a durable, lasting cure for HS, significantly reducing disease morbidity.

摘要

化脓性汗腺炎(HS)是一种慢性复发性皮肤炎症性疾病,其特征为反复出现引流性窦道和脓肿,主要发生在有终毛和顶泌汗腺的皮肤褶皱处。针对这种使人衰弱的疾病的治疗方法一直是使用抗生素和免疫调节剂进行药物治疗。随着更好的重建外科技术的出现,手术在HS治疗中的作用得到了扩展,从最后的手段转变为更早应用的一种治疗方式。更大的缺损可以更容易地进行重建,从而能够更彻底地切除病变区域。使用筋膜皮组织的局部皮瓣、穿支皮瓣和推进皮瓣能够用相似的组织重建缺损,并提供更好的美容和功能效果。它们易于实施,甚至在资源匮乏的环境中,结合使用免疫调节剂和术后抗生素也可以进行。由于对疾病行为的认识、多学科护理以及先进重建技术的进步,HS在早期阶段以及严重疾病时都可以通过手术成功治疗。与多学科护理团队相结合,手术为HS提供了持久、彻底的治愈方法,显著降低了疾病的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7cee7c7ad566/gox-12-e5860-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/2e91e20b389a/gox-12-e5860-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/d56f3c8c9685/gox-12-e5860-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7a20af7d999c/gox-12-e5860-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/4e3807bfdfb2/gox-12-e5860-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/34239f929d88/gox-12-e5860-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7d8fe46facc4/gox-12-e5860-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7cee7c7ad566/gox-12-e5860-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/2e91e20b389a/gox-12-e5860-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/9a6a7a2a2f9e/gox-12-e5860-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/d56f3c8c9685/gox-12-e5860-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7a20af7d999c/gox-12-e5860-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/4e3807bfdfb2/gox-12-e5860-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/34239f929d88/gox-12-e5860-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7d8fe46facc4/gox-12-e5860-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd1/11175856/7cee7c7ad566/gox-12-e5860-g008.jpg

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2
Surgical Management of Hidradenitis Suppurativa: A Narrative Review.化脓性汗腺炎的外科治疗:一项叙述性综述
J Clin Aesthet Dermatol. 2022 Jan;15(1):35-41.
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Impact of a hidradenitis suppurativa patient decision aid on treatment decision making: A randomized controlled trial.化脓性汗腺炎患者决策辅助工具对治疗决策的影响:一项随机对照试验。
专家提供的化脓性汗腺炎综合更新管理算法
Am J Clin Dermatol. 2025 Apr 3. doi: 10.1007/s40257-025-00940-0.
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Hidradenitis suppurativa, from basic science to surgery and a new era of tailored targeted therapy: An expert opinion paper.化脓性汗腺炎:从基础科学到外科手术及量身定制的靶向治疗新时代:一篇专家意见论文
Arch Dermatol Res. 2025 Feb 28;317(1):511. doi: 10.1007/s00403-025-04016-1.
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