Faculty of Engineering and Built Environment, School of Electrical Engineering and Computer Science, the University of Newcastle, NSW 2308, Australia.
Phys Med Biol. 2014 Jan 6;59(1):61-81. doi: 10.1088/0031-9155/59/1/61. Epub 2013 Dec 12.
A new tool has been developed to verify the trajectory of dynamic multileaf collimators (MLCs) used in advanced radiotherapy techniques using only the information provided by the electronic portal imaging devices (EPID) measured image frames. The prescribed leaf positions are resampled to a higher resolution in a pre-processing stage to improve the verification precision. Measured MLC positions are extracted from the EPID frames using a template matching method. A cosine similarity metric is then applied to synchronise measured and planned leaf positions for comparison. Three additional comparison functions were incorporated to ensure robust synchronisation. The MLC leaf trajectory error detection was simulated for both intensity modulated radiation therapy (IMRT) (prostate) and volumetric modulated arc therapy (VMAT) (head-and-neck) deliveries with anthropomorphic phantoms in the beam. The overall accuracy for MLC positions automatically extracted from EPID image frames was approximately 0.5 mm. The MLC leaf trajectory verification system can detect leaf position errors during IMRT and VMAT with a tolerance of 3.5 mm within 1 s.
已经开发出一种新工具,仅使用电子射野影像装置(EPID)测量图像帧提供的信息,即可验证先进放疗技术中使用的动态多叶准直器(MLC)的轨迹。在预处理阶段,将规定的叶片位置重新采样到更高的分辨率,以提高验证精度。使用模板匹配方法从 EPID 帧中提取测量的 MLC 位置。然后应用余弦相似度度量来同步测量和计划的叶片位置以进行比较。还合并了三个附加的比较函数,以确保稳健的同步。在射束中使用人体模体模拟了强度调制放射治疗(IMRT)(前列腺)和容积调制弧形治疗(VMAT)(头颈部)的 MLC 叶片轨迹误差检测。从 EPID 图像帧中自动提取的 MLC 位置的整体精度约为 0.5 毫米。MLC 叶片轨迹验证系统可以检测 IMRT 和 VMAT 期间的叶片位置误差,在 1 秒内容忍 3.5 毫米的误差。