Department of Ophthalmology, University of Southern California, Keck School of Medicine, Los Angeles, California.
Invest Ophthalmol Vis Sci. 2013 Dec 13;54(14):ORSF1-4. doi: 10.1167/iovs.13-12993.
This volume presents articles based on a workshop held June 14 to 16, 2013 in Rancho Palos Verde, CA sponsored by the Ocular Research Symposia Foundation (ORSF). The mission of the ORSF is to focus attention on unmet needs and current research opportunities in eye research with the objective of accelerating translation of research findings to effective clinical care. In this workshop, the subject of the "The Aging Eye" was addressed, including the prevalence of eye diseases in aging and the economic burden imposed by these diseases. New research work was highlighted on the genetics, biology, biochemistry, neurochemistry, and the impact of nutrition and the environment on function in the older eye. By identifying "low-hanging fruit" (i.e., the best opportunities for successful transition of laboratory research for the prevention of and new treatments and cures for ocular diseases), we seek to spur funding at both the basic research and clinical levels, resulting in sight-saving and sight-restoration measures in the near future.
本卷收录了基于 2013 年 6 月 14 日至 16 日在加利福尼亚州 Rancho Palos Verde 举行的研讨会的文章,该研讨会由眼研究座谈会基金会(ORSF)主办。ORSF 的使命是关注眼睛研究中未满足的需求和当前的研究机会,目的是加速研究成果向有效临床护理的转化。在本次研讨会上,探讨了“衰老的眼睛”这一主题,包括衰老过程中眼部疾病的流行情况以及这些疾病带来的经济负担。重点介绍了遗传学、生物学、生物化学、神经化学方面的新研究工作,以及营养和环境对老年眼睛功能的影响。通过确定“低挂果实”(即成功将实验室研究转化为预防和治疗眼部疾病的新疗法和治愈方法的最佳机会),我们寻求刺激基础研究和临床研究层面的资金投入,以期在不久的将来采取挽救和恢复视力的措施。