de Brauw L M, van de Velde C J, Bouwhuis-Hoogerwerf M L, Zwaveling A
J Surg Oncol. 1987 Feb;34(2):81-6. doi: 10.1002/jso.2930340204.
Clinical features and their prognostic value were evaluated in 83 colorectal cancer patients with liver metastasis. The clinical features analysed included presenting symptoms and signs, liver function tests, extent of liver involvement, associated extrahepatic tumor growth, and physical condition of the patients. Overall median survival time after diagnosis of liver metastases was 8.4 months. Prognostic factors related to survival were symptoms, when referable to liver metastasis, and 5' Nt. Information is supplied to survey what selection of patients should be considered for various treatment options. A predominance of the patients showed bilobar liver involvement (79.6%), extrahepatic tumor growth (49.4%), or had an unresectable primary tumor (30.1%), thus leaving only 6% of the patients with liver metastases for surgical treatment with the intention of cure.
对83例发生肝转移的结直肠癌患者的临床特征及其预后价值进行了评估。分析的临床特征包括出现的症状和体征、肝功能检查、肝脏受累程度、相关的肝外肿瘤生长情况以及患者的身体状况。诊断肝转移后的总体中位生存时间为8.4个月。与生存相关的预后因素是可归因于肝转移的症状和5′核苷酸酶。提供信息以调查对于各种治疗方案应考虑选择哪些患者。大多数患者表现为双侧肝脏受累（79.6%）、肝外肿瘤生长（49.4%）或有不可切除的原发肿瘤（30.1%），因此仅有6%发生肝转移的患者适合接受旨在治愈的手术治疗。
